ID   E1EZE1_GIAIA            Unreviewed;       497 AA.
AC   E1EZE1;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Transglutaminase-like domain-containing protein {ECO:0000259|SMART:SM00460};
GN   ORFNames=GLP15_937 {ECO:0000313|EMBL:EFO64399.1};
OS   Giardia intestinalis (strain P15) (Giardia lamblia).
OC   Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX   NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO64399.1, ECO:0000313|Proteomes:UP000008974};
RN   [1] {ECO:0000313|EMBL:EFO64399.1, ECO:0000313|Proteomes:UP000008974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P15 {ECO:0000313|EMBL:EFO64399.1,
RC   ECO:0000313|Proteomes:UP000008974};
RX   PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA   Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA   Andersson J.O., Svard S.G., Andersson B.;
RT   "Genome analysis and comparative genomics of a Giardia intestinalis
RT   assemblage E isolate.";
RL   BMC Genomics 11:543-543(2010).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFO64399.1}.
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DR   EMBL; ACVC01000096; EFO64399.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1EZE1; -.
DR   EnsemblProtists; EFO64399; EFO64399; GLP15_937.
DR   VEuPathDB; GiardiaDB:GLP15_937; -.
DR   OMA; CACEGYA; -.
DR   OrthoDB; 316032at2759; -.
DR   Proteomes; UP000008974; Unassembled WGS sequence.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR46333; CYTOKINESIS PROTEIN 3; 1.
DR   PANTHER; PTHR46333:SF2; TRANSGLUTAMINASE-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
FT   DOMAIN          220..295
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          18..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   497 AA;  55765 MW;  3CE8A850B2CA5784 CRC64;
     MNGKHITSVA ITSSKPSNYL SSTGSVETQS KIRLGGPSSR ESRSVNQLGA GVAQAAATSF
     VGYTDLEKVF GVSMKYRYHR SIFTGPLRKC YDYILHVVVS IRSPTIHIPE DCSGVTDAEV
     EKIRTAINYD FPELYGVQIT KTVRIQKRLH SIKIVYDPSF HMINDVLDKI DRLLVSTLNK
     KISENPNQTD YVREMTTVSW MKSHCKYDAK GPNRSNITGF FFNKHCACEG YARSFLFLCN
     RLGIPCIFVT GRSNGPLVPS DSSGGGPSSS PQSERGHCWN MVQIEGIWYY TDITWCSVVG
     LRHPDTGKVV FPNYFINISK DLYDILHVED HPFPLPSNPP NMPLDVRLRH NYYFLTGFVW
     TVSFDNHKTS LEKNTKNTGT AATSEIMIPN ESVVSLCKLL LMAISKGKQF VEVLIRIGNQ
     DPFGLHTVTM RNMLKDPRLW TLVNAVLEET QQLNKYISPC AVMVPQGNYP AAMVFFKLVS
     SKPKITSGGK PKVYTRN
//