ID E1F081_GIAIA Unreviewed; 1810 AA.
AC E1F081;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Liver stage antigen-like protein {ECO:0000313|EMBL:EFO64138.1};
GN ORFNames=GLP15_444 {ECO:0000313|EMBL:EFO64138.1};
OS Giardia intestinalis (strain P15) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO64138.1, ECO:0000313|Proteomes:UP000008974};
RN [1] {ECO:0000313|EMBL:EFO64138.1, ECO:0000313|Proteomes:UP000008974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P15 {ECO:0000313|EMBL:EFO64138.1,
RC ECO:0000313|Proteomes:UP000008974};
RX PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA Andersson J.O., Svard S.G., Andersson B.;
RT "Genome analysis and comparative genomics of a Giardia intestinalis
RT assemblage E isolate.";
RL BMC Genomics 11:543-543(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFO64138.1}.
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DR EMBL; ACVC01000104; EFO64138.1; -; Genomic_DNA.
DR STRING; 658858.E1F081; -.
DR EnsemblProtists; EFO64138; EFO64138; GLP15_444.
DR VEuPathDB; GiardiaDB:GLP15_444; -.
DR OMA; EEEIWAF; -.
DR OrthoDB; 5482530at2759; -.
DR Proteomes; UP000008974; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR037831; SNX17/27/31-like.
DR PANTHER; PTHR12431:SF14; LD15323P; 1.
DR PANTHER; PTHR12431; SORTING NEXIN 17 AND 27; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 1693..1803
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 151..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 758..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1422..1441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 854..881
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1006..1184
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1212..1247
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1322..1397
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 151..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..632
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1425..1440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1810 AA; 201285 MW; 72E678273B2CF4E8 CRC64;
MEDIAYTDGY AAQYGDNYAY DGYGYGGDLA VGDYNPYGTD YGYDAGGYDY GAGYGGYENQ
NAGYGEQIYG YGGPVEQQQE SLSLKLNEPK SVSEQEYGGS PVVHTDATSA AMDPFSAGMD
AVTEPVGSQI RTSSAFPPVS QDLLNSIRVQ QETSGNLSKS PSKISSRPAS ARLDELDKVI
EEDAEQLTKE PTTDAPIADA APDTADMFGF IEQPADSVTA AEPVTINDDD VFGFGPEGDV
HGAPVQSKVE GVEPDAEAPS AEAEDDMFGF TRSPQETVAG ASADSTAPTA EPVDDMFGFA
GPVVESAATA EPDTIEGDDM FGFDPIESTP EDHDTGVSEA IKDVTADAQD AADNMFGFGE
IGSPTEAPTQ SANIAASPVV DLKEDSMFGF DSPPAPADNT TTAPLDDSAG DMFGFEPAAL
EMQSEPVPED QDVAQVPADS MFGFDLPTDV SATIEPPAAG LATNELETPP ADDMFGFSPN
ETAVATAKLD EGQEIAPVNA KTLDESQSVT NGYTQPTAGP SDDMFGFGNS VDPLQIDSVP
PSGAIADDMF GFDSASATET PVRPPPEKPE LSDASQTQTA LDLPTIPDHI PAIEDDQASL
SHESTPHESH HESQIASEEH DQLKEVSETL EVGKMDKQPA QESVAEDMFG FGDALTSAED
SLTEKTTESR QTELPTLADL PPPVSASSLL PVQTLESAKQ PAIPADTPVA DMAIDIDSMI
SAALVPQQPS LVPEQKVENQ IRDEPQLSVP IAELPPVAEE ESLEEANEEF AAESQREPVE
LSEGRSLGND IELAVQVPLP PEEDTQDVLA EPIVPAEILE RLAIDETFIK LQAELQFTYL
MPEPNREELE KLQVTDHEQQ LIQLKDEAER LQTENRVLAG RSAVSRHLHP NEFDSKSISV
SFFEGLLNEP TNSDGVSLTT GEELRLLAIL EQGNYEALDA LHGMSSEELQ LMEQREREFN
LKLKELTDRR DELLYKDDTE ALKLIEEEIW AFVDAEEEKK MRLQAADDLL KKRAQEEEDR
RRAEIEAKIK EEQDRVAEER RLQEEMIVLQ KKQQQEYAEQ ETRKADLLRE AMEKEQLERI
EEEQRIKAEA RRRLIDDLEA TAERAAAEDR IRVKAELEEM ARIKKELEDA ARTASEEKRK
LLLQQKEQLE REMAETARRH EEDVARRHKE LQALHEERRK MREQRLASSE PMHELLREDG
NDASTDPFSY ASLDIERRIK EMKAQLEKEM AEKIALEHAD LNALEQELAA KKLSTLQAER
LLNTVASDTV ARLDDEDRLF NESMDAKRQE LLLLKEQYGL MRHQNESQRA LHLEEQVKAE
KLARLIEQVA ELAEKKHKLE RKIAHESKEF HKKESKLVAS NSKGALKALR KEHAKEHEAL
ETQLASISEQ LRKAKKQLKA LSPQKGAPDI DRSLSVKDYL RSTDKNETGQ GLSTADREHS
QPRLSVFEGG SLGQPSLVSG HGIGTVMSAT TDHGDGGKKH HVSSGLPAAL QKLREEHARR
LEKIEQRRVT FASEREQLQA QTHALEAQLS KPVNVPDSKL RTREQRKQII FAEMNRMEKL
SKAHMVEVKP QIPEKTIDEI LNERRKRHGE EREQLKNMAV RFTSAYDRHS RVSVNMDSSD
DEWNDLATQT SSRYANLSTK PRSMQAQVRQ FASDRIDPVF NSYIEAPVRP GYESSLLSYV
KVSSDPTTCH PTKFVARLTA HTWCVEQKSK PYVVYTFMIS TERGVFEVAK RFSELRELDK
SLRRVFPTVT LPKYPSSMGG KFTDEQLEER KRLLGRYMSQ LNQIAVIRTS QVYKEFMQMK
VKHDILVYHR
//
