ID   E1F9A2_GIAIA            Unreviewed;       844 AA.
AC   E1F9A2;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=Rubicon Homology domain-containing protein {ECO:0000259|Pfam:PF13901};
GN   ORFNames=GLP15_3299 {ECO:0000313|EMBL:EFO60942.1};
OS   Giardia intestinalis (strain P15) (Giardia lamblia).
OC   Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX   NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO60942.1, ECO:0000313|Proteomes:UP000008974};
RN   [1] {ECO:0000313|EMBL:EFO60942.1, ECO:0000313|Proteomes:UP000008974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P15 {ECO:0000313|EMBL:EFO60942.1,
RC   ECO:0000313|Proteomes:UP000008974};
RX   PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA   Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA   Andersson J.O., Svard S.G., Andersson B.;
RT   "Genome analysis and comparative genomics of a Giardia intestinalis
RT   assemblage E isolate.";
RL   BMC Genomics 11:543-543(2010).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFO60942.1}.
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DR   EMBL; ACVC01000476; EFO60942.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1F9A2; -.
DR   EnsemblProtists; EFO60942; EFO60942; GLP15_3299.
DR   VEuPathDB; GiardiaDB:GLP15_3299; -.
DR   OMA; FTGFCES; -.
DR   OrthoDB; 5478491at2759; -.
DR   Proteomes; UP000008974; Unassembled WGS sequence.
DR   InterPro; IPR025258; RH_dom.
DR   Pfam; PF13901; RH_dom; 1.
PE   4: Predicted;
FT   DOMAIN          685..842
FT                   /note="Rubicon Homology"
FT                   /evidence="ECO:0000259|Pfam:PF13901"
FT   REGION          189..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        189..238
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   844 AA;  92863 MW;  1A329DC0041F0DBA CRC64;
     MSVHDLSETD LVDALDFLIE YVRYGEEGHG SIWTDKDPVT QRLAEVLACI LVKGSKGEYI
     WTSIREYIEQ NFQDPLRILP ILTSNPELQQ ADEQIKILAL TRLLLTEDQF IGLFTGFCES
     IMPEMYPEPS IVGHTKRRGK VIKYLMRMHD SGARFQLALF PPADVAPGTL AEYQLAAING
     KRLYKEQAGL NSSQPSTTPS SISSSAIRAT ELSQPAPPTP SIAQSSAPAT SLGPSVSEPQ
     PDENPKDQKF ESKLTIDFTK PELLPVPAPA PLLVEDGLVF ERHSEISFQQ NNLSSAASME
     KKPPCSAISE PPLPLVKPAT VVTPVTVPTP QKPSIPVPEP PKPSVQLPAP KLSGYTPAQA
     LSLDTMADDA ALLKSLTKSS SVQVIAGVPV NISSVQNRDA ITNRVAQPSP LKAAPVPTVS
     QTMQLEARTI ESKLSSTSIP SDIAPTKDNF LASTLPAPTN NHKPEVEEVK TIFTRTNLLT
     DANKSLLGDT CPTIKDEIKK IEKRVAVVET IIDKKTIENE GLVMDVLSDI PVERAVLSEK
     GDCEMVSFTG KALITDGIVN YWVRLATLVT ESDGFKKTDK SKHKGKQDKD LGVVPSAPAC
     SNKTFLFNIE HYTFDKIAAG TSNFATPLLC AENAPSINTY TYILTDYSRP PNLSKLISGL
     QANKCAGCDC SLANISQEEQ TDLLFCHYIG KIYCKQCSLI VNKHIIPSKV LSSKRDTMEY
     TVGAASYKTL EKYWKQPNLE TTYLLSIRMD LDTVFNGCLQ KRTKLFQRFR SRDNCASLAR
     IFSMVENQAY YYTQHIQSDG TQNFYWSMSD IVSILLNKQI ALVEKLYNEI QAHSATCATC
     QAIF
//