ID E1QJZ7_DESB2 Unreviewed; 2142 AA.
AC E1QJZ7;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=DNA helicase related protein {ECO:0000313|EMBL:ADK85890.1};
GN OrderedLocusNames=Deba_2535 {ECO:0000313|EMBL:ADK85890.1};
OS Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / LMG 7858 / VKM B-1802
OS / 2st14).
OC Bacteria; Thermodesulfobacteriota; Desulfarculia; Desulfarculales;
OC Desulfarculaceae; Desulfarculus.
OX NCBI_TaxID=644282 {ECO:0000313|EMBL:ADK85890.1, ECO:0000313|Proteomes:UP000009047};
RN [1] {ECO:0000313|EMBL:ADK85890.1, ECO:0000313|Proteomes:UP000009047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33931 / DSM 2075 / LMG 7858 / VKM B-1802 / 2st14
RC {ECO:0000313|Proteomes:UP000009047};
RX PubMed=21304732; DOI=10.4056/sigs.1243258;
RA Sun H., Spring S., Lapidus A., Davenport K., Del Rio T.G., Tice H.,
RA Nolan M., Copeland A., Cheng J.F., Lucas S., Tapia R., Goodwin L.,
RA Pitluck S., Ivanova N., Pagani I., Mavromatis K., Ovchinnikova G., Pati A.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C.,
RA Han C., Rohde M., Brambilla E., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Land M.;
RT "Complete genome sequence of Desulfarculus baarsii type strain (2st14).";
RL Stand. Genomic Sci. 3:276-284(2010).
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DR EMBL; CP002085; ADK85890.1; -; Genomic_DNA.
DR RefSeq; WP_013259329.1; NC_014365.1.
DR STRING; 644282.Deba_2535; -.
DR KEGG; dbr:Deba_2535; -.
DR eggNOG; COG1112; Bacteria.
DR eggNOG; COG1198; Bacteria.
DR HOGENOM; CLU_000788_0_1_7; -.
DR OrthoDB; 9757917at2; -.
DR Proteomes; UP000009047; Chromosome.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 3.40.960.10; VSR Endonuclease; 1.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR021754; DUF3320.
DR InterPro; IPR025103; DUF4011.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF11784; DUF3320; 1.
DR Pfam; PF13195; DUF4011; 1.
DR Pfam; PF18741; MTES_1575; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:ADK85890.1};
KW Helicase {ECO:0000313|EMBL:ADK85890.1};
KW Hydrolase {ECO:0000313|EMBL:ADK85890.1};
KW Nucleotide-binding {ECO:0000313|EMBL:ADK85890.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009047}.
FT DOMAIN 680..749
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1491..1530
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1553..1749
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT DOMAIN 1799..1895
FT /note="Restriction endonuclease type II-like"
FT /evidence="ECO:0000259|Pfam:PF18741"
FT DOMAIN 1999..2037
FT /note="DUF3320"
FT /evidence="ECO:0000259|Pfam:PF11784"
FT REGION 1917..1958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1917..1933
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2142 AA; 239159 MW; CF960059A039CC7A CRC64;
MDFLPQSTSD LTIESTFAPK VSFALHQNSV PVLLELAIRN DGQAPWEDLD LTLHSDPAFF
RSRSWRISKL NPEQRYSIVD LDLQLDGGQL FRLTEAEKGQ ILFELRQGDT VLCRSEKPVE
LLARNQWGGL GQFPELAAAF VRPNDPAVDR VLKKAADLLL TAGKESALEG YAKGGKQRAW
EIMSAVWQAV CSLGLDYALP PAGFEQQGQK VRSPERIVSN GLATCLDLSF LFASCLEQCQ
LNPLLVFLEG HAFAGAWLVP EIFATTMIDD VSALRKRLQL QEILLFEPTL VVRGQQEPAK
FTWACQVGTH QVSEEEPRPF HLALDIRRAR MERIRPLASE EVPISPASTE TSATQVPDLL
NLDDAPDLME VETQVRPSDQ LRPQDRLDRW QRKLLDLSLR NNLLNFRSSK RVVELMVPNP
GRLEDLLADG KRFKLRPGVR PMQGTDPRDE ALHQARHREE VGREHAMEGL GRGELFTRLS
EEEMESRLVE LFRASRLALQ EGGANTLYLV LGFLVWNQGG KDARRLRAPL ILIPVSLARQ
AVRSGFSLAL HEDEPRFNLT LLEMLRQDFH LRLPALEGEL PRDDSGLDVA TIWRTMATAI
KDMAGWEVAE DVCLGQFSFA KYLMWKDLAV HADQLRQNPV VHHLIDTPTQ AYGDRTRFVP
PERLDDVLPP SRNFCPLPAD SSQLAAVVAA ANGQDFVLEG PPGTGKSQTI ANLIAQCLAL
DKTVLFVAEK TAALEVVYRR LKTIGLGEFC LELHSHKANK LEVLKQLRQS WEARADADQA
TWDEESARMG SLRDQLNALV ERLHHRWPNG LCVFAAISKT LAGRDMPQLP LRWSAPESHD
KASLDALLDI ATRLGINATE VAGAAGGDLA LVTGTEWSPG WETSLTAALR EMLPVCEEMQ
RTSTAFFSAT GLPEIALSES VRRALVELAD MLPEAFGRDW SFLARPDAPD ILSRLSEGLA
LVARRQALTA ELREQDARLA EFADSHGGPS ELWPGLEDTV QNILADLRAC LPRIERGLEP
SQGIAGEEPM SGRLDTLRGQ LTTLTAEVRN TTQTFFARLR DGQALETRRR QLWGQLSRNY
RPEALGIDLE GLRLVWQEAE NAWWPKNALG RSRVRKALAA VTEAGRSNQS NEAQDLDVLL
DIRRLDTKLA AFEDLQDQSS GEWPWAERQA AGQAAFDHLK EGLTLAANYF NLLTKIQEQD
ARLAAYADLG KLTSGLWSGL TTRSQDIEFA RDLGERLKIC LSGLYDRPES LGPGVEALKR
LLGENNLLLS PSGAVTRTGA DFATMARHYE PARTTMASLL GNEESKRGEL EAMLPDVLAE
RCQVILSRTR LLRAWCAWNR VVGEARAQGL HSLVEALTKG ELAGDQAREA FTVNYCRWWL
CAAVDADPLL RRFVSVEHEQ AIEDFRRLDQ KLADLARNCI RARLRNGTPG IGDARNAPEW
GLLRREMEKK RRHLPLRQLM EQIPTALPSL TPCLLMSPLS IAQYLPPGRT SFDLVVFDEA
SQIPVWDAIG AMARGKQVVV VGDPKQMPPT NFFNRAEDED ADDEVEIGGD MESILDECCG
AGLPRQRLNW HYRSRHESLI AFSNHRYYGG SLVTFPSPLT DDRAVSLQFV EGAFYDKGGS
RTNQAEAKAV VADIVRHLAD PAFVENGKSI GVVTFNTQQQ KLIEDLLDEE RRRDPDLDRF
FSDELTEPIF VKNLENVQGD ERDLMYFSIT YGPDQAGRVS MNFGPLNKDG GERRLNVAVT
RAKHALKIFT CLLPDRMDLS RTRAKGVADL KLFLEYARRG IKALAEEATT PRGDFDSPFE
EIVAEALSRR GWTAHPQVGV STFRVDLGVV DPDRPGRYLA GVECDGAAYH RAATARDRDR
LREQVLRDLG WEIVRTWSTD WWHDAETAAN KLDASLRKIL ECTREETARI ERERCRQVAE
KVSEEKSAKR IEQSSPFGDR PAEPLPDPVP PAQATETASQ PVLAELYAKR STEDQALSET
ATPEPAIRDI LADGEEVELA AAIREIMAVE GPIRADVLAR RIAKRCGLHK AGSRIREKVL
QVAEREFKGI KEDGALFLWP TDTIPGQWDR FRATVNDESR PADEICLAEL VALARDVASQ
VAPEEDPVMV MARAMGLQRL RAVTRARLEK AWEASRSSCP AN
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