ID E1QRH9_VULDI Unreviewed; 975 AA.
AC E1QRH9;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Glycoside hydrolase family 38 {ECO:0000313|EMBL:ADN51793.1};
GN OrderedLocusNames=Vdis_2427 {ECO:0000313|EMBL:ADN51793.1};
OS Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 /
OS IC-017).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Vulcanisaeta.
OX NCBI_TaxID=572478 {ECO:0000313|EMBL:ADN51793.1, ECO:0000313|Proteomes:UP000006681};
RN [1] {ECO:0000313|EMBL:ADN51793.1, ECO:0000313|Proteomes:UP000006681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14429 / JCM 11212 / NBRC 100878 / IC-017
RC {ECO:0000313|Proteomes:UP000006681};
RX PubMed=21304741;
RA Mavromatis K., Sikorski J., Pabst E., Teshima H., Lapidus A., Lucas S.,
RA Nolan M., Glavina Del Rio T., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA Liolios K., Ivanova N., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Spring S.,
RA Goker M., Wirth R., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Vulcanisaeta distributa type strain (IC-
RT 017).";
RL Stand. Genomic Sci. 3:117-125(2010).
RN [2] {ECO:0000313|Proteomes:UP000006681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14429 / JCM 11212 / NBRC 100878 / IC-017
RC {ECO:0000313|Proteomes:UP000006681};
RX DOI=10.4056/sigs.1113067;
RA Mavromatis K., Sikorski J., Pabst E., Teshima H., Lapidus A., Lucas S.,
RA Nolan M., Glavina Del Rio T., Cheng J., Bruce D., Goodwin L., Pitluck S.,
RA Liolios K., Ivanova N., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y., Jeffries C., Rohde M., Spring S., Goker M.,
RA Wirth R., Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P.,
RA Klenk H., Kyrpides N.;
RT "Complete genome sequence of Vulcanisaeta distributa type strain (IC-
RT 017T).";
RL Stand. Genomic Sci. 3:117-125(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
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DR EMBL; CP002100; ADN51793.1; -; Genomic_DNA.
DR AlphaFoldDB; E1QRH9; -.
DR STRING; 572478.Vdis_2427; -.
DR CAZy; GH38; Glycoside Hydrolase Family 38.
DR KEGG; vdi:Vdis_2427; -.
DR eggNOG; arCOG03661; Archaea.
DR HOGENOM; CLU_003442_1_0_2; -.
DR Proteomes; UP000006681; Chromosome.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000313|EMBL:ADN51793.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006681}.
FT DOMAIN 492..563
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 975 AA; 110827 MW; 3C6775DC57AA5794 CRC64;
MFVGFDLRDV GGVRTKLFYL EAASIMGVDA VNLEACGGAL CGSVVVRDFG EPWFFVDVVG
EGTLRVDDLQ FAVFNYGDEG ESRWVRASPG RHSLSLVLSP VRMFGERRVS FNGMYVVYRE
PSLFSFVLRA KLLLDVAEAF EDLRTDYLKV LNEALDAVPL DSVANWQLEF AVRAHIVEPP
GFVRALFNYY DAKELTHLRP PDFSELGRAA KEGLRILEEG IEGLRVRRGH RGVVYVAGHA
HIDLGWLWSR DVTREKVRRT IINVLSLLQS YPELTFLVSN MAYLRWLSED RDLWVRVREA
VKAGRIVPVG GMWVESDANL PGGESLVRQF LYGQRFLLRG FGFTTEIGWL PDTFGFPASL
PQILRKAGIR VFFEHKMYWN TVNRFPYSVF LWEGIDGSVI PTINYATYGA DLTPRQIARA
WSDHTSPELP AFLPFGKGDG GGGPTWLMLE RYRVYRDLPG MPRLIMGNLK DLISEVVRDD
SLPRWRGELY LEIHRGVYTN GIRLKQLVRA LETKLRELET FSVIAGVRRS YEELWYPLLE
AEYHDPMGAT STKSVYDEVV NELEEDLKRV DGELMNVLRK TLGTGCFVTI VNPLPWARRE
LVMVREELSG VATQRVGNGY LALIEVPALG WRSFEKGPGN SMGDVTVGSN YVENSVVRVV
FDGSLRIYDK EVGRWAVEDG YLMACEDMPS RWDGWDIDAY YRRVCRRLEP TGFSVVEGGP
LRGCIEVNYR FRESSIRQRI CVNAFSRRVD VENEVDWRER LTLLKAVYKL GIFGHSASFE
VPYGVVNRPT RPSNTWEVAK FEVPALRWVD VWDPDYGVAI LNDGRQGYSV EENTVTITLL
RSPIYPNPFL DYGHNKFTYA IYPHSGDWRT AQVPRRAYEF NQPLIIVEGT AGGDSSFLEI
TNPAIMLEAL KWGEDSGIVL RLYETYGVNT CTEVRGFIKG EGVETDLLEL NNYGNADLGN
LCFRPFEIKT ILVKS
//
