ID E1QUM3_VULDI Unreviewed; 396 AA.
AC E1QUM3;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:ADN51142.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:ADN51142.1};
GN OrderedLocusNames=Vdis_1768 {ECO:0000313|EMBL:ADN51142.1};
OS Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 /
OS IC-017).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Vulcanisaeta.
OX NCBI_TaxID=572478 {ECO:0000313|EMBL:ADN51142.1, ECO:0000313|Proteomes:UP000006681};
RN [1] {ECO:0000313|EMBL:ADN51142.1, ECO:0000313|Proteomes:UP000006681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14429 / JCM 11212 / NBRC 100878 / IC-017
RC {ECO:0000313|Proteomes:UP000006681};
RX PubMed=21304741;
RA Mavromatis K., Sikorski J., Pabst E., Teshima H., Lapidus A., Lucas S.,
RA Nolan M., Glavina Del Rio T., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA Liolios K., Ivanova N., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Spring S.,
RA Goker M., Wirth R., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Vulcanisaeta distributa type strain (IC-
RT 017).";
RL Stand. Genomic Sci. 3:117-125(2010).
RN [2] {ECO:0000313|Proteomes:UP000006681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14429 / JCM 11212 / NBRC 100878 / IC-017
RC {ECO:0000313|Proteomes:UP000006681};
RX DOI=10.4056/sigs.1113067;
RA Mavromatis K., Sikorski J., Pabst E., Teshima H., Lapidus A., Lucas S.,
RA Nolan M., Glavina Del Rio T., Cheng J., Bruce D., Goodwin L., Pitluck S.,
RA Liolios K., Ivanova N., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y., Jeffries C., Rohde M., Spring S., Goker M.,
RA Wirth R., Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P.,
RA Klenk H., Kyrpides N.;
RT "Complete genome sequence of Vulcanisaeta distributa type strain (IC-
RT 017T).";
RL Stand. Genomic Sci. 3:117-125(2010).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982}.
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DR EMBL; CP002100; ADN51142.1; -; Genomic_DNA.
DR RefSeq; WP_013336867.1; NC_014537.1.
DR AlphaFoldDB; E1QUM3; -.
DR STRING; 572478.Vdis_1768; -.
DR GeneID; 9752711; -.
DR KEGG; vdi:Vdis_1768; -.
DR eggNOG; arCOG01282; Archaea.
DR HOGENOM; CLU_031026_0_0_2; -.
DR OrthoDB; 25212at2157; -.
DR Proteomes; UP000006681; Chromosome.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:ADN51142.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006681};
KW Transferase {ECO:0000313|EMBL:ADN51142.1}.
FT DOMAIN 5..264
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 273..394
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
SQ SEQUENCE 396 AA; 42742 MW; 792B797358739264 CRC64;
MSQDIVITGF VRTPIGKFGG AFKNVKTPYL AAEAIKALIR RTGIEGKLID EVVFGSTLQG
GMGQNLSRFA ALLAGLPIEV SAFTVNRVCS SGMQAIIEAV RALKVGDVNV VIAGGAESMS
TQPLALPHEV RWGIKHLIGR DLRFIDLMIY DGLTDPTNMM LMGQEADKVA MEHEITREEL
DKVAYESHMR ALKATENKYY LELEPVDTVI NGERVYLDRD EGIRPDTSLE KLAKLKPAFG
PNGLHTAGNS SQLSDGAAAL LLTTMDKAKE IGLKPIARIV GYAWHMLEPW RFPEAPIYVI
RKLLSKVGWS INDVDVFEVN EAFAVVNVLV NKELGIPYDK MNIFGGAIAL GHPLGASGAR
IVTTLISALI HVGGKRGVAA LCHGTGGATA LAIEML
//
