ID E1RCX4_METP4 Unreviewed; 738 AA.
AC E1RCX4;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Multi-sensor signal transduction histidine kinase {ECO:0000313|EMBL:ADN35874.1};
GN OrderedLocusNames=Mpet_1108 {ECO:0000313|EMBL:ADN35874.1};
OS Methanolacinia petrolearia (strain DSM 11571 / OCM 486 / SEBR 4847)
OS (Methanoplanus petrolearius).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanolacinia.
OX NCBI_TaxID=679926 {ECO:0000313|EMBL:ADN35874.1, ECO:0000313|Proteomes:UP000006565};
RN [1] {ECO:0000313|EMBL:ADN35874.1, ECO:0000313|Proteomes:UP000006565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11571 / OCM 486 / SEBR 4847
RC {ECO:0000313|Proteomes:UP000006565};
RX PubMed=21304750;
RA Brambilla E., Djao O.D., Daligault H., Lapidus A., Lucas S., Hammon N.,
RA Nolan M., Tice H., Cheng J.F., Han C., Tapia R., Goodwin L., Pitluck S.,
RA Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Rohde M.,
RA Spring S., Sikorski J., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Methanoplanus petrolearius type strain (SEBR
RT 4847).";
RL Stand. Genomic Sci. 3:203-211(2010).
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DR EMBL; CP002117; ADN35874.1; -; Genomic_DNA.
DR RefSeq; WP_013329052.1; NC_014507.1.
DR AlphaFoldDB; E1RCX4; -.
DR STRING; 679926.Mpet_1108; -.
DR GeneID; 25394983; -.
DR KEGG; mpi:Mpet_1108; -.
DR eggNOG; arCOG06192; Archaea.
DR eggNOG; arCOG06193; Archaea.
DR eggNOG; arCOG06712; Archaea.
DR eggNOG; arCOG06940; Archaea.
DR HOGENOM; CLU_000445_114_58_2; -.
DR Proteomes; UP000006565; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 3.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ADN35874.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006565};
KW Transferase {ECO:0000313|EMBL:ADN35874.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 121..166
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 207..260
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 261..331
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 335..387
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 395..441
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 464..520
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 531..734
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 738 AA; 84010 MW; F5D90D1124992A42 CRC64;
MKKSDIKPVW TPKIAPVYLI TASTLLAIAI SIISLMNGCF IIFQNFFYIP IVIACIYYGK
KGFFFSILIS AIYFILISVF TQNPEIIYDA LIRVCIFIFI AGVTTYLSIK QKCTEEELTN
AEQKLDDIIE FLPDPIFLID TDKRVIAWNR AMEKVAGIPK DDIVGKGDSA YSEAIYGNKK
PVLIDAVISG DILDSRYKNL KKEGDTVSAE IHFDSENEKD ITDFRVTASP FYDTNGKVIG
AVEYIHDITE LKRNETVLRE NEAYLRTLIR TIPDLVWLKD EKGVFISCNK MFERFFGATE
EEIKGKTDYD FLDHELADFF RENDRRAVEA GGPTTNEEWI TFADDGHRAC LETIKTPMYD
SDGKLIGVLG IGRDITLRKE MEDALRESEA KLMILNKDLN TIFENAPAMI FYKDTKNKFI
RVNPKVAEKF GLPVEDIVGR SGRDLFPHYK DAYYEDDLKI INSGEPEFGI IESFITAKGK
KLWISMDKIP LKDQNGEVYG VLLFATDITE QKKNQDALKE VNRKLNLLSS ITRHDILNQI
TVAAGYLDLI EMDQNIPKET KTEEYINKIT NAVETIKRQI TFTGYYKDLG EQSPQWFDVG
EIIEKISTSS AFVSDIKSIK FTNNIENIEV FADPLFEKVI YNLTDNAIKH GETITEITFY
SEQKPDELII YCEDDGVGIP GDVKEKIFRR EYFKNSGLGL FLSREILSIT GLTITETGTP
GEGARFEIHI PEGKFRAK
//
