ID E1SS10_FERBD Unreviewed; 1047 AA.
AC E1SS10;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Efflux pump membrane transporter {ECO:0000256|RuleBase:RU364070};
GN OrderedLocusNames=Fbal_1762 {ECO:0000313|EMBL:ADN75965.1};
OS Ferrimonas balearica (strain DSM 9799 / CCM 4581 / KCTC 23876 / PAT).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Ferrimonadaceae; Ferrimonas.
OX NCBI_TaxID=550540 {ECO:0000313|EMBL:ADN75965.1, ECO:0000313|Proteomes:UP000006683};
RN [1] {ECO:0000313|EMBL:ADN75965.1, ECO:0000313|Proteomes:UP000006683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9799 / CCM 4581 / KCTC 23876 / PAT
RC {ECO:0000313|Proteomes:UP000006683};
RX DOI=10.4056/sigs.1161239;
RA Nolan M., Sikorski J., Davenport K., Lucas S., Glavina Del Rio T., Tice H.,
RA Cheng J., Goodwin L., Pitluck S., Liolios K., Ivanova N., Mavromatis K.,
RA Ovchinnikova G., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y., Jeffries C., Tapia R., Brettin T., Detter J., Han C.,
RA Yasawong M., Rohde M., Tindall B., Goker M., Woyke T., Bristow J.,
RA Eisen J., Markowitz V., Hugenholtz P., Kyrpides N., Klenk H., Lapidus A.;
RT "Complete genome sequence of Ferrimonas balearica type strain (PAT).";
RL Stand. Genomic Sci. 3:174-182(2010).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU364070}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU364070}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942,
CC ECO:0000256|RuleBase:RU364070}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364070}.
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DR EMBL; CP002209; ADN75965.1; -; Genomic_DNA.
DR RefSeq; WP_013345271.1; NC_014541.1.
DR AlphaFoldDB; E1SS10; -.
DR STRING; 550540.Fbal_1762; -.
DR GeneID; 67181967; -.
DR KEGG; fbl:Fbal_1762; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_1_6; -.
DR OrthoDB; 9757904at2; -.
DR Proteomes; UP000006683; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042908; P:xenobiotic transport; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004764; MdtF-like.
DR NCBIfam; TIGR00915; 2A0602; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF13; MULTIDRUG EFFLUX PUMP SUBUNIT ACRB-RELATED; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364070};
KW Cell membrane {ECO:0000256|RuleBase:RU364070};
KW Membrane {ECO:0000256|RuleBase:RU364070};
KW Reference proteome {ECO:0000313|Proteomes:UP000006683};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364070};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364070}; Transport {ECO:0000256|RuleBase:RU364070}.
FT TRANSMEM 340..359
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 366..390
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 438..459
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 465..488
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 538..554
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 870..888
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 894..914
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 970..990
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 1002..1024
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
SQ SEQUENCE 1047 AA; 112612 MW; 2694B32A2A0EF347 CRC64;
MANFFIDRPV FAWVLAILAM LAGILSLVQL PVAQYPNIAP PAIQVTAFYP GASAKTAEET
VTQVIEQELT GLDGLRYISS ESDSFGNSII TLTFEAGTDP DIAQVQVQNK VSGATAKLPE
VVQRQGVVVE KSSDTFLMVM AFYSTDGSMT DTDLSDFVAS NLEDPISRVP GVGSVQLFGA
EYAMRIWLDP NRLESYGLNP SDVTAAIAEQ NTQVSAGQLG ATPVVEGQQL NATITARSLL
RTPEEFEGIL LKVEEDGSEV RIRDVARVEL GAANYSTIAR YNGQPASGMG ISLATGANAL
DTMNAVNDRI AELRNLFPPG VEMQVPYDTT PFVKLSIENV VHTLLEAVVL VFLVMFLFLQ
SFRATLIPTI AIPVVVLGTM AVLMALGYSI NTLTMFAMVL AIGLLVDDAI VVVEGVERVM
EEEGLPPLEA TRKSMKQLSG ALVGIGMVLS AVFVPMAFFG GTTGIIYRQF SITIVTAVAL
SVLVALILTP TLCVQLMKQG HGSGSDKGFF GWFNRTFDRA TNGYVGHVDG FIRRMGRLML
IFVALAAVAG YLMTRLPTSF LPDEDQGVMI GMVMLPTGST QAQTVDVLKQ AEDYFLTNET
EAVASVFSVA GFSFAGRGAN AGILFMNMVP FKERTTEESS VWAVMGRAQR AFSQIKEAMV
FVFAPPAIIE LGTATGFDMY LQDRTGLGHD ALMQGRNQLL GMAMQNPNLM NVRPNGLDDT
PQFVIEIDQL KAEALGVSIN DINNTLTTSF GSAYVNDFID RGRVKQVYVQ SDAQYRMVPS
DIDFWYVRNN QGEMVPLKAI TSTRWEFGSP RLERFNGVSA MQIQGQPKAG ISTGVAMTTM
EQLVSQLPNN LNVAWTGLSY EEREAGGQAG ALYVLSILIV FLCLAALYES WSVPFSVILV
VPLGVLGAVI ATGLRGLDND VYFQVGLLTT VGLSAKNAIM IVEFAKQYYE EGADMVEAAL
HAARVRLRPI LMTSLAFGFG VLPLALSSGA GSGAQNAVGT GVIGGVITAT FLGVFFVPLF
FVFVSRLAHR KQTSPPAPEA PAQEGAV
//
