ID E1TDN3_BURSG Unreviewed; 473 AA.
AC E1TDN3;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Integral membrane sensor signal transduction histidine kinase {ECO:0000313|EMBL:ADN61159.1};
GN OrderedLocusNames=BC1003_5239 {ECO:0000313|EMBL:ADN61159.1};
OS Burkholderia sp. (strain CCGE1003).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=640512 {ECO:0000313|EMBL:ADN61159.1};
RN [1] {ECO:0000313|EMBL:ADN61159.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCGE1003 {ECO:0000313|EMBL:ADN61159.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Daligault H., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G.,
RA Martinez-Romero E., Rogel M.A., Auchtung J., Tiedje J.M., Woyke T.;
RT "Complete sequence of chromosome2 of Burkholderia sp. CCGE1003.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002218; ADN61159.1; -; Genomic_DNA.
DR AlphaFoldDB; E1TDN3; -.
DR STRING; 640512.BC1003_5239; -.
DR KEGG; bgf:BC1003_5239; -.
DR eggNOG; COG4564; Bacteria.
DR HOGENOM; CLU_000445_20_6_4; -.
DR OrthoDB; 9797605at2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR033480; sCache_2.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR InterPro; IPR017171; Sig_transdc_His_kinase_MctS.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF37; SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE UHPB; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF17200; sCache_2; 1.
DR PIRSF; PIRSF037314; STHK_MctS; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ADN61159.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 206..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 256..458
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 232..260
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 473 AA; 51607 MW; C5BE72CC32A0CCA3 CRC64;
MKLKAKIVLL AIVPFLAAIS SIEIGVRREA TALAQAQHAT TQAAYMASKE IELKHYVELA
TSAIAPLYEE DQDNARDDAL RRTRALGILE KMDFGKDGYF FVYDTHGRSL MHPREPDLVG
RDLSELRDPE GVPTIQKLLA AAAQGGGYVR YLWHRPSTGK MASKLGYVVP LQRWGWMIGT
GIYLDDVDTT LADIDQRAAT NIDRTMMWID TIALAGLAAI ALCALVLNIT EYRSADAKLK
RLAQQVVESQ ENERARLSRE LHDGISQMMV SVKLLLESAL ARFERSETRV PAAEAALSTS
LTRLGDTLRE IRRISHALRP SMLDDLGVAA AIEQLTRELG EQSGIEIGFT QITHTHAASL
TDAVNTVLFR IAQEALTNIV RHAHASNAAL ALEISNDAVT LSIADNGRGF DVTHAFVGRR
SGVGLRNMRE RVEALGGTLA LSSQPGHTLV TARVPLGAAA MEGDRQSLQE TSS
//
