ID E1TF01_BURSG Unreviewed; 267 AA.
AC E1TF01;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Ureidoglycolate lyase {ECO:0000256|ARBA:ARBA00019751};
DE EC=4.3.2.3 {ECO:0000256|ARBA:ARBA00012341};
DE AltName: Full=Ureidoglycolase {ECO:0000256|ARBA:ARBA00032843};
DE AltName: Full=Ureidoglycolatase {ECO:0000256|ARBA:ARBA00030302};
DE AltName: Full=Ureidoglycolate hydrolase {ECO:0000256|ARBA:ARBA00029968};
GN OrderedLocusNames=BC1003_4297 {ECO:0000313|EMBL:ADN60231.1};
OS Burkholderia sp. (strain CCGE1003).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=640512 {ECO:0000313|EMBL:ADN60231.1};
RN [1] {ECO:0000313|EMBL:ADN60231.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCGE1003 {ECO:0000313|EMBL:ADN60231.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Daligault H., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G.,
RA Martinez-Romero E., Rogel M.A., Auchtung J., Tiedje J.M., Woyke T.;
RT "Complete sequence of chromosome2 of Burkholderia sp. CCGE1003.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-ureidoglycolate = glyoxylate + urea; Xref=Rhea:RHEA:11304,
CC ChEBI:CHEBI:16199, ChEBI:CHEBI:36655, ChEBI:CHEBI:57296; EC=4.3.2.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001281};
CC -!- PATHWAY: Purine metabolism; urate degradation.
CC {ECO:0000256|ARBA:ARBA00004705}.
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DR EMBL; CP002218; ADN60231.1; -; Genomic_DNA.
DR AlphaFoldDB; E1TF01; -.
DR STRING; 640512.BC1003_4297; -.
DR KEGG; bgf:BC1003_4297; -.
DR eggNOG; COG0179; Bacteria.
DR HOGENOM; CLU_028458_4_2_4; -.
DR OrthoDB; 8582489at2; -.
DR UniPathway; UPA00394; -.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050385; F:ureidoglycolate lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0019628; P:urate catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR PANTHER; PTHR11820:SF115; FUMARYLACETOACETATE HYDROLASE; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ADN60231.1};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 55..253
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 267 AA; 28127 MW; AC049CB25CB0A9F1 CRC64;
MDTWMRFMSN DGGVVFGRVE GAYLHEYESL DQPVPTGAVL STRALTPLAP CAPGKIVALW
NNFHALAAKL DKPVPTHPLF LLKPAGSAIG SGEAIRRPAS YAGKIVYEGE LGIVIGRRCR
DASVEEAAAA IFGYTLVNDV TAADLLNENP HFPQWCRAKG FDTFCCIGPA IVSGFDWQSA
HLVTVLDGVE RQNYPLSDMV FSPAEQVSLI SQDLTLEPGD VIACGTSVGV GSIKDGATVS
VSIDGIGTLS NTLRAALAVA AEVPGLV
//
