ID E1THN5_BURSG Unreviewed; 742 AA.
AC E1THN5;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Exopolysaccharide transport protein family {ECO:0000313|EMBL:ADN59539.1};
DE EC=2.7.10.2 {ECO:0000313|EMBL:ADN59539.1};
GN OrderedLocusNames=BC1003_3598 {ECO:0000313|EMBL:ADN59539.1};
OS Burkholderia sp. (strain CCGE1003).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=640512 {ECO:0000313|EMBL:ADN59539.1};
RN [1] {ECO:0000313|EMBL:ADN59539.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCGE1003 {ECO:0000313|EMBL:ADN59539.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Daligault H., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G.,
RA Martinez-Romero E., Rogel M.A., Auchtung J., Tiedje J.M., Woyke T.;
RT "Complete sequence of chromosome2 of Burkholderia sp. CCGE1003.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
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DR EMBL; CP002218; ADN59539.1; -; Genomic_DNA.
DR AlphaFoldDB; E1THN5; -.
DR STRING; 640512.BC1003_3598; -.
DR KEGG; bgf:BC1003_3598; -.
DR eggNOG; COG0489; Bacteria.
DR eggNOG; COG3206; Bacteria.
DR HOGENOM; CLU_009912_0_0_4; -.
DR OrthoDB; 9808257at2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR005700; EPS_ExoP-like.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR NCBIfam; TIGR01005; eps_transp_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR Pfam; PF02706; Wzz; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ADN59539.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 542..695
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 742 AA; 80921 MW; D02D0DB59E187D9B CRC64;
MNNRIDMTVG DPVDDDADLI RYVDVLVGSR WLIAGICAVI LAIGVAYAFL ARPNYEANIM
IQVEEDNPTS ATSLLGDVSS LFDVKTQAEG EVEILQSRAV VDQAVNDLRL YIDAAPRRFP
LIGWLIADHD KSLSNPGLFG MGGFCWGGES ISVEQFEVPS DLVGKRFKLT LLDNNRFRVT
QSDLDAPIEG VVGEPVVSNQ SIGQFRLLVS HVSGKPGAVF SLTRYSKLLT LEALQKKLTV
EQKGKQSDII TASLRGRDPQ QITAILNSLG SAYVAQNIKR KAAEADKSAA FLEGLLPGLK
HDVEQAEQRY NAFRNSKGTY DLGLEAQTLL QETVAWQTNL LTLQQKRAEL SSGYSPDHPS
VRAVEQQIAA MKARLQAVDG RMKSLPNLEQ GTVALMRDVQ VNTDVYLGAL NNLQQLKLVS
AGKVGNVRQV DTARVPEEPV QPKKPLVIGL ALIAGLMIGV ATAFAREHFY GGITDVQDIE
RYAGLNVYGA IPYSAEQRTL DEAIRTRRSG LALLAAARPD EPSIESLRSL RTALRFAMLD
APNNRLLLTG PGPGVGKSFI ASNLAAIMAS SDKRVILVDA DMRRGYLNQY FGVSRGKGLS
NVLSGEATLD EVIRRDVAEG LDLITTGSIP PNAAELLMSE TMNRLMQRLS ERYDLVVIDA
PPVLAVADAG IIAGNAGTTF LIARFQRTVI GELTESARHL QRANATLKGV IFNAVDARAF
GYRSKYGSYR YVAYRYDRKL TK
//
