ID E1VAV8_HALED Unreviewed; 2374 AA.
AC E1VAV8;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN OrderedLocusNames=HELO_4173 {ECO:0000313|EMBL:CBV44057.1};
OS Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198
OS / 1H9).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=768066 {ECO:0000313|EMBL:CBV44057.1, ECO:0000313|Proteomes:UP000008707};
RN [1] {ECO:0000313|Proteomes:UP000008707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9
RC {ECO:0000313|Proteomes:UP000008707};
RX PubMed=20849449; DOI=10.1111/j.1462-2920.2010.02336.x;
RA Schwibbert K., Marin-Sanguino A., Bagyan I., Heidrich G., Lentzen G.,
RA Seitz H., Rampp M., Schuster S.C., Klenk H.P., Pfeiffer F., Oesterhelt D.,
RA Kunte H.J.;
RT "A blueprint of ectoine metabolism from the genome of the industrial
RT producer Halomonas elongata DSM 2581(T).";
RL Environ. Microbiol. 13:1973-1994(2011).
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DR EMBL; FN869568; CBV44057.1; -; Genomic_DNA.
DR STRING; 768066.HELO_4173; -.
DR KEGG; hel:HELO_4173; -.
DR eggNOG; COG2911; Bacteria.
DR eggNOG; COG5126; Bacteria.
DR HOGENOM; CLU_001019_0_0_6; -.
DR OrthoDB; 6144932at2; -.
DR Proteomes; UP000008707; Chromosome.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 6.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR10827:SF51; CALCIUM-BINDING PROTEIN 4A-RELATED; 1.
DR PANTHER; PTHR10827; RETICULOCALBIN; 1.
DR Pfam; PF13202; EF-hand_5; 2.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 13.
DR SUPFAM; SSF47473; EF-hand; 6.
DR PROSITE; PS00018; EF_HAND_1; 6.
DR PROSITE; PS50222; EF_HAND_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 1394..1429
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1439..1465
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1529..1564
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1664..1699
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1734..1769
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1804..1839
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1943..1978
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT COILED 405..432
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2025..2069
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2304..2338
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2374 AA; 256211 MW; FAE30128566E4E53 CRC64;
MDKNFKTGLI ITGNADGGVR AVRATSSEIR NLNRDFESGS KRARSYGHET RQTARELEFL
KQHALGVGTA IAGAFAANNL AQQAVMIRNT DALANSLQVN TKTLQEWQFA GRSVGLEADK
IGDIFKDVSD KLGDFAATGG GEAKDLFENL NLNIRELQAL SPDKQILRIA DAINEIEDPS
QRSFYFESLA DEMVRLQPLL ANGAQGLREA SDMADALGIA MDDIEVRRAV EAAEAMDQLQ
GVAQGLSNTL IADLGPGLAD STRSLTEFID EVGGADEVLE GIGQTITMLG SVYLAVRLRK
PLSKIGPLGL AAGRNIAQGF AMAVGASGRL NQALVVTQGR IAATAAAGRA LRSSLALIGG
PAGAALLAAG GIYTFREELG LTIPRADASS EAVHQLTGKL NDLNKAAAEK KLTELNNRLA
DLKASAEETG QAYLEVGKND TGHGGFLGAD VSGQVEKIQE IGEGAKESRQ EMANVEEAIG
LVRDRLEHLN STGERTPPVL TNIGDASEDA AKKLEKQKEA AKSLLDELYP VLASQREYAE
QKELLTQYAE REGKSNQWLE ESLSRLQNQY RNAGSAAEVY GFDGSKAMEK VEDSVDPMAT
AFERGIERMD DAAVDMWRSF LDGSEGAFDS FKNLALDTLA EVIHAYTTRQ ITTSIGAQIG
IGGQGASTAG GGGGFGNIAS IGKQVYSGVV DGFSSVAWTG ASNTAYAGGW AGSATSGIGQ
SGFMGGSLSN FGGSTGLMSL GASMIGSEVG DAVSGALTDK QANSNWGQMA GSAIGTYFGG
PIGAGLGSAL GSVVDSLFGS GGSDLDLAMV RGRDESAHTW DHGIVAQGGL GAVGFQDEGS
HEVADLWDID EAKQLVESIA QLDTAVASLA ETPEQLAAMR DAVMASNRHG IQGHYGETSN
PGDVVDRLTS RYDDAFGALD AEFAEFMQGL DGSIDQVLEK GIAARQAFTF LSDASERLDL
RFNDTTASAY EAAASLAEAA GGVQNLSSLQ QNYYQTLYSE EERLNQLRSD VTQQLNAMGM
SLPTSREGFR QLVEAQNLNT EAGRENYVQL MQLVDSFDRL RESASSVNDE TTDLADKISG
LKDDVKSAWE TFDKQSFDQR ITLLEMAGKS EEALALQRER ELATIDESLR PFQERIWALQ
DEAKAQEEAA QAGKEYAQAL ADAQSWLGST LENITGWIDR NQSTDAGMGS PADQLAAAGE
AYREQLEAAR GGDRTALQNI TQYADRFIAA QKQWSASGGD TTSLIDRIER QLGTLPDQLS
AEEYIADEIK QALIEQTAGI TSELADVLRS DTPSNIAGAL ASSFDDLTRG IGDVLTREQL
ATVMAGKATD AQLDAVMRVV DLNGDGVMSG LESVIIKSMP TDATLANALR QQLQANGDKA
LTAAQVRQAL RPIASDKRIN QLIRRVDTNG DGLLSAQELT SSRLGGLADG IAASLSGSFD
QLDANLDDNL TFDELKDGLS GMATDAQLKA LMRSMDVNAD GVISGLESVV IESMPTDSRL
ANVLRNQLKW TRNQQLTHDQ VREALRPIAS DESISQLIRR LDTNGDGIIT AQEVGNARLG
GLADGIAASL SGSFDQLDAN LDDNLTFAEL KDGLSGMATD AQLKALMRSM DVNADGVISG
LESVVIESMP TDSRLANVLR NQFKWTRNQQ LTADQVRDAL KGKASNDRIN QLIRRADKNA
DGIIDAAELA SDVTTSELSS VLAKQLGWTR NQIKWTRNSQ LTADQVRDAL KGKASNERIN
QLIRRADKNA DGIIDAAELA SDVTTSELSG VLAKQLGWTR DQIKWTRNSQ LTANQVRDAL
KGKASNDRIN QMIRRADKNA DGIIDATELA SDASTSELSQ VLSNQLKWTR NQIKWTRNSQ
LTHDQVREAL SPIASNAEID RLITRLDKNS DGIISAQEMA SERLDGLASG IGNALSPMFD
TIDRSLDGLI DYDEFGKSFA GMASDEQLKR IFAQLDKNGD GTISRLEAMK GSTDEVGDNT
ASIEQQSLNQ LEKLNNLVGE MTRTTDQFVD MNSTMVSLRD SINALGVAQE EQNRIERERR
EAKERQEKRL EKERAAASYL DRANQLEQQA QDKTLFDNLD GITAKRSDVI VGNIMDQAGN
DNILSWKEYQ SALDDMKDRR DKGWYNAGEL DFAKTAALSL RKQSRYHEMM DQAAGITGDD
YSGSIDRPDF AGVREELKGL SDIERARSFF TRYSDYAGSW KIWRGTLDYD WDRWTGNILT
TPIADADLIR VAKELDRDFA GPKRFFAKGG VFTNSVVDQP TMFNMGVMGE AGPEAVMPLA
NGPEGLGIRL YDTPPIPELP LLGRDDIAET LRDVLRENRQ LRKDLNRLMG ENNEHAAAGV
AVSQEGFKRV DRNTARIAET NDAIDDRQRL EAQR
//
