ID   E1VJP7_9GAMM            Unreviewed;       110 AA.
AC   E1VJP7;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Quaternary ammonium compound resistance protein {ECO:0000313|EMBL:CBL45039.1};
GN   Name=qacE2 {ECO:0000313|EMBL:CBL45039.1};
GN   ORFNames=HDN1F_14560 {ECO:0000313|EMBL:CBL45039.1};
OS   gamma proteobacterium HdN1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria.
OX   NCBI_TaxID=83406 {ECO:0000313|EMBL:CBL45039.1, ECO:0000313|Proteomes:UP000002677};
RN   [1] {ECO:0000313|EMBL:CBL45039.1, ECO:0000313|Proteomes:UP000002677}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HdN1 {ECO:0000313|Proteomes:UP000002677};
RA   Widdel F., Rabus R., Grundmann O., Werner I., Schreiber F., Ehrenreich P.,
RA   Behrends A., Wilkes H., Kube M., Reinhardt R., Zedelius J.;
RT   "Alkane degradation by a new type of denitrifying bacterium with possible
RT   involvement of the electron acceptor in substrate activation.";
RL   Environ. Microbiol. 0:0-0(2010).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC       {ECO:0000256|ARBA:ARBA00038032, ECO:0000256|RuleBase:RU003942}.
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DR   EMBL; FP929140; CBL45039.1; -; Genomic_DNA.
DR   AlphaFoldDB; E1VJP7; -.
DR   STRING; 83406.HDN1F_14560; -.
DR   KEGG; gpb:HDN1F_14560; -.
DR   eggNOG; COG2076; Bacteria.
DR   HOGENOM; CLU_133067_0_2_6; -.
DR   OrthoDB; 9808638at2; -.
DR   Proteomes; UP000002677; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   PANTHER; PTHR30561:SF1; MULTIDRUG TRANSPORTER EMRE; 1.
DR   PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002677};
KW   Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        32..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   110 AA;  11405 MW;  357FC9A262E77157 CRC64;
     MNWLLLGIAI LSEVIATSAL KSSEGFTRLW PSVIVIAGYT SAFYFLSLTL KSIPIGIAYA
     VWSGAGVALI AVIGWVMFGQ KLDFAAGIGI GLIVAGVVVL NVFSGASSHS
//