ID E1VJW2_9GAMM Unreviewed; 448 AA.
AC E1VJW2;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Peptidase M12A domain-containing protein {ECO:0000259|Pfam:PF01400};
GN ORFNames=HDN1F_15210 {ECO:0000313|EMBL:CBL45104.1};
OS gamma proteobacterium HdN1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria.
OX NCBI_TaxID=83406 {ECO:0000313|EMBL:CBL45104.1, ECO:0000313|Proteomes:UP000002677};
RN [1] {ECO:0000313|EMBL:CBL45104.1, ECO:0000313|Proteomes:UP000002677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HdN1 {ECO:0000313|Proteomes:UP000002677};
RA Widdel F., Rabus R., Grundmann O., Werner I., Schreiber F., Ehrenreich P.,
RA Behrends A., Wilkes H., Kube M., Reinhardt R., Zedelius J.;
RT "Alkane degradation by a new type of denitrifying bacterium with possible
RT involvement of the electron acceptor in substrate activation.";
RL Environ. Microbiol. 0:0-0(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FP929140; CBL45104.1; -; Genomic_DNA.
DR AlphaFoldDB; E1VJW2; -.
DR STRING; 83406.HDN1F_15210; -.
DR KEGG; gpb:HDN1F_15210; -.
DR HOGENOM; CLU_610790_0_0_6; -.
DR Proteomes; UP000002677; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR001506; Peptidase_M12A.
DR Pfam; PF01400; Astacin; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00023049};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00023049};
KW Reference proteome {ECO:0000313|Proteomes:UP000002677};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..219
FT /note="Peptidase M12A"
FT /evidence="ECO:0000259|Pfam:PF01400"
SQ SEQUENCE 448 AA; 48754 MW; E5E391AEE22D5585 CRC64;
MMASASVFAL SMDANRNKQI LWPEGSVPYL ITKDKDLSAE DEARMRPIVL QRIADWNNVG
DNGKYLNLFP ISQEQTVEYP TYLAIDLRPK SNLTDCGAVS QHVNKNGGAE NASGYPGIDS
FARIALPASC PGAITHEIGH VIGFKHEQTR KDSNIVLNFC NYRISNPDSA DCRYKSATAN
GSAQTLWANE SAPKPSFYLS DYDPFSIMHY SLQNNLKKEL IGKIDPSTGY YYTTIDFNSD
PKKENNVQSL ANRFAGGSIG DLYAQLLNRS TVFSAGDVSS VRKAYAKNTS DVHVSFVRTC
FNKDKPEQIG ECDTKRFRAT ATVSNFGAYP AKDVKLRITH EGKNLEPDSF VVSGERCTME
SAQVALCDFG TVNPNSSGSK VAVTGVVADV KVAAVVSANV SSSTPQNAQL LDEKQFDAKV
SAGGGSIGFW GILAGFGLLV SRRRRRVA
//
