ID E1VMG0_9GAMM Unreviewed; 565 AA.
AC E1VMG0;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Putative glutathione-regulated potassium-efflux system K+/H+ antiporter {ECO:0000313|EMBL:CBL46002.1};
GN ORFNames=HDN1F_24190 {ECO:0000313|EMBL:CBL46002.1};
OS gamma proteobacterium HdN1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria.
OX NCBI_TaxID=83406 {ECO:0000313|EMBL:CBL46002.1, ECO:0000313|Proteomes:UP000002677};
RN [1] {ECO:0000313|EMBL:CBL46002.1, ECO:0000313|Proteomes:UP000002677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HdN1 {ECO:0000313|Proteomes:UP000002677};
RA Widdel F., Rabus R., Grundmann O., Werner I., Schreiber F., Ehrenreich P.,
RA Behrends A., Wilkes H., Kube M., Reinhardt R., Zedelius J.;
RT "Alkane degradation by a new type of denitrifying bacterium with possible
RT involvement of the electron acceptor in substrate activation.";
RL Environ. Microbiol. 0:0-0(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FP929140; CBL46002.1; -; Genomic_DNA.
DR AlphaFoldDB; E1VMG0; -.
DR STRING; 83406.HDN1F_24190; -.
DR KEGG; gpb:HDN1F_24190; -.
DR eggNOG; COG0475; Bacteria.
DR eggNOG; COG1226; Bacteria.
DR HOGENOM; CLU_005126_9_0_6; -.
DR OrthoDB; 9781411at2; -.
DR Proteomes; UP000002677; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR46157; K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC; 1.
DR PANTHER; PTHR46157:SF4; K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000002677};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 406..528
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 565 AA; 60836 MW; 758F4A039C1ACD08 CRC64;
MMEHLAQILL LLAVTIAVIV TFQRLKIPTS LGYLLVGVIL GPYTFGPTVR VPEFDALAEF
GVVFLLFTIG LNYSLPQLQA LRGQVLGQGT GQVVFTTIFG GIIMWLAGLP VAVAFVFGAV
FAQSSTTVIG SLLAEQGEDN TRHGRLGLAM SVFQDVTAVP FLVIIPVLGA SVAASALALT
LGWALAKAVF AFALVFFAGR WLLGPLLHLV SQRQSLEIFT LAVLLVALLS AWTTNSLGLS
LAFGGFLAGM MLGESEFRHQ IESSIRPFRD VLLGLFFIGI GMRFDPMAIP PIWQWTVACA
LLIIVSKIVL VTVIVHRSTK DPRLAFRTGL MLSVGGEFGL ALIAIALDSS TINLEQGQIL
ITSVLLAMVG GAVLIRFNRT LAGWLFRAPQ QENAAEAELP EGANTLVVIG GYGRVGHTIA
VLLASHGVPF VAFDPDPQRV LQGRTDGHRV YYGSISDPEL LATIHIERAS LVVLTVDDVD
KALPAISYLR QMCPQVPVIA RARDLLASTR LQEAGAVHSY PETIEASLRL GAMALQILEI
STTEIEQTLQ GVRDWGYRPV LEEPE
//
