ID E1Z3S9_CHLVA Unreviewed; 588 AA.
AC E1Z3S9;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Eukaryotic peptide chain release factor GTP-binding subunit {ECO:0000256|ARBA:ARBA00015765};
DE AltName: Full=ERF2 {ECO:0000256|ARBA:ARBA00030845};
DE AltName: Full=Polypeptide release factor 3 {ECO:0000256|ARBA:ARBA00029585};
DE AltName: Full=Translation release factor 3 {ECO:0000256|ARBA:ARBA00030210};
DE Flags: Fragment;
GN ORFNames=CHLNCDRAFT_29643 {ECO:0000313|EMBL:EFN59534.1};
OS Chlorella variabilis (Green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX NCBI_TaxID=554065 {ECO:0000313|Proteomes:UP000008141};
RN [1] {ECO:0000313|EMBL:EFN59534.1, ECO:0000313|Proteomes:UP000008141}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NC64A {ECO:0000313|EMBL:EFN59534.1,
RC ECO:0000313|Proteomes:UP000008141};
RX PubMed=20852019; DOI=10.1105/tpc.110.076406;
RA Blanc G., Duncan G., Agarkova I., Borodovsky M., Gurnon J., Kuo A.,
RA Lindquist E., Lucas S., Pangilinan J., Polle J., Salamov A., Terry A.,
RA Yamada T., Dunigan D.D., Grigoriev I.V., Claverie J.M., Van Etten J.L.;
RT "The Chlorella variabilis NC64A genome reveals adaptation to
RT photosymbiosis, coevolution with viruses, and cryptic sex.";
RL Plant Cell 22:2943-2955(2010).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; GL433836; EFN59534.1; -; Genomic_DNA.
DR RefSeq; XP_005851636.1; XM_005851574.1.
DR AlphaFoldDB; E1Z3S9; -.
DR STRING; 554065.E1Z3S9; -.
DR GeneID; 17358541; -.
DR KEGG; cvr:CHLNCDRAFT_29643; -.
DR eggNOG; KOG0459; Eukaryota.
DR InParanoid; E1Z3S9; -.
DR OMA; GKMESGC; -.
DR OrthoDB; 5477300at2759; -.
DR Proteomes; UP000008141; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03704; eRF3_C_III; 1.
DR CDD; cd04089; eRF3_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF36; TR-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008141}.
FT DOMAIN 166..399
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 26..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..84
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 588
FT /evidence="ECO:0000313|EMBL:EFN59534.1"
SQ SEQUENCE 588 AA; 63066 MW; 14CFAAE25A465F03 CRC64;
MADSWEDHQE EKVVYKPAAL NPSAASFSFS PGASSFTPNF APQAAAAAPA PPPAAPAPPP
APPPAPVQPA APAPPPPAPE PEPAPEASGG AADGAADKPA AVAAAAPPAP AAAAPAPVEA
VAKEVKKMSV ASGGDGDVLQ ETDAQREARH AQVKQTVAEM NTEDPREHLN IVFIGHVDAG
KSTTAGQILF LTGGVDDRTI EKYEREAKEK NRESWYMAYI MDTNEEERAK GKTVEVGRAY
FETPKKRYTV LDAPGHKSFV PNMIGGASQA DIGVLIISAR KGEFETGFER GGQTREHAQL
AKTLGVTKLV VAINKMDDHS VLEEGGKSKE RFDEIEGKLT PFLRGCGYNP KKDLLFIPIS
GLMGTNMKQK VSADVCSWYS GPCLFDLLDN IEAAGRDPFA PFRMPIMDRY KDMGTVVMGK
SEAGVVKKGD TLMVMPNKVP VKVLTVYRDE QEVNAARPGE NLRLRLQGIE EEDISAGNRF
SPVPAVTQFE AQVVIMELLD HKPILTGGYK AVLHIHSVVE ECEVTKLVAV IDPKTKEKKK
AKFAKSGAMC VARIAVEKPI CIETFDHVPQ LGRFTLRDEG KTIAIGKV
//
