ID E1Z3Y5_CHLVA Unreviewed; 280 AA.
AC E1Z3Y5;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=3-oxoacyl-[acyl-carrier-protein] reductase {ECO:0000256|ARBA:ARBA00012948};
DE EC=1.1.1.100 {ECO:0000256|ARBA:ARBA00012948};
DE Flags: Fragment;
GN ORFNames=CHLNCDRAFT_19172 {ECO:0000313|EMBL:EFN59256.1};
OS Chlorella variabilis (Green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX NCBI_TaxID=554065 {ECO:0000313|Proteomes:UP000008141};
RN [1] {ECO:0000313|EMBL:EFN59256.1, ECO:0000313|Proteomes:UP000008141}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NC64A {ECO:0000313|EMBL:EFN59256.1,
RC ECO:0000313|Proteomes:UP000008141};
RX PubMed=20852019; DOI=10.1105/tpc.110.076406;
RA Blanc G., Duncan G., Agarkova I., Borodovsky M., Gurnon J., Kuo A.,
RA Lindquist E., Lucas S., Pangilinan J., Polle J., Salamov A., Terry A.,
RA Yamada T., Dunigan D.D., Grigoriev I.V., Claverie J.M., Van Etten J.L.;
RT "The Chlorella variabilis NC64A genome reveals adaptation to
RT photosymbiosis, coevolution with viruses, and cryptic sex.";
RL Plant Cell 22:2943-2955(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+)
CC + NADPH; Xref=Rhea:RHEA:17397, Rhea:RHEA-COMP:9916, Rhea:RHEA-
CC COMP:9945, ChEBI:CHEBI:15378, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:78776, ChEBI:CHEBI:78827; EC=1.1.1.100;
CC Evidence={ECO:0000256|ARBA:ARBA00001572};
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
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DR EMBL; GL433836; EFN59256.1; -; Genomic_DNA.
DR RefSeq; XP_005851358.1; XM_005851296.1.
DR AlphaFoldDB; E1Z3Y5; -.
DR STRING; 554065.E1Z3Y5; -.
DR GeneID; 17358446; -.
DR KEGG; cvr:CHLNCDRAFT_19172; -.
DR eggNOG; KOG0725; Eukaryota.
DR InParanoid; E1Z3Y5; -.
DR OMA; DIACCNA; -.
DR OrthoDB; 565at2759; -.
DR Proteomes; UP000008141; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR42879; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE; 1.
DR PANTHER; PTHR42879:SF2; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG; 1.
DR Pfam; PF00106; adh_short; 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008141}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFN59256.1"
SQ SEQUENCE 280 AA; 30011 MW; A647D36F7CD34AB5 CRC64;
GSTTGIGMGI LKQLAAGGAI TVMHGLETEE NILQKAAAVQ AKYGNTVGTS TANLLNPQEI
RDMVARVQEE FGKLDILVNN AGIQYVAPVH EFPEEKWNAI IDVILNAPFH ATKAALPAMI
DAGWGRVVNT GTPPPPHLCR RYPGRSMHAL VASPFKSAYN AAKHGIAGFT KTVALEVATK
GVTCNAVCPG YVMTELIEKQ LANQAKTRGI PKARDPCFLY CLFLLLLQEK VITDVLLVDQ
PIKRFVKPEE VGSLVRHLCT DDAAAITGAC LSIDGGWTAR
//
