ID E1Z4M0_CHLVA Unreviewed; 663 AA.
AC E1Z4M0;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=CNNM transmembrane domain-containing protein {ECO:0000259|PROSITE:PS51846};
GN ORFNames=CHLNCDRAFT_137839 {ECO:0000313|EMBL:EFN59369.1};
OS Chlorella variabilis (Green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Chlorella clade; Chlorella.
OX NCBI_TaxID=554065 {ECO:0000313|Proteomes:UP000008141};
RN [1] {ECO:0000313|EMBL:EFN59369.1, ECO:0000313|Proteomes:UP000008141}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NC64A {ECO:0000313|EMBL:EFN59369.1,
RC ECO:0000313|Proteomes:UP000008141};
RX PubMed=20852019; DOI=10.1105/tpc.110.076406;
RA Blanc G., Duncan G., Agarkova I., Borodovsky M., Gurnon J., Kuo A.,
RA Lindquist E., Lucas S., Pangilinan J., Polle J., Salamov A., Terry A.,
RA Yamada T., Dunigan D.D., Grigoriev I.V., Claverie J.M., Van Etten J.L.;
RT "The Chlorella variabilis NC64A genome reveals adaptation to
RT photosymbiosis, coevolution with viruses, and cryptic sex.";
RL Plant Cell 22:2943-2955(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL433836; EFN59369.1; -; Genomic_DNA.
DR RefSeq; XP_005851471.1; XM_005851409.1.
DR AlphaFoldDB; E1Z4M0; -.
DR STRING; 554065.E1Z4M0; -.
DR GeneID; 17358530; -.
DR KEGG; cvr:CHLNCDRAFT_137839; -.
DR eggNOG; KOG2118; Eukaryota.
DR InParanoid; E1Z4M0; -.
DR OrthoDB; 306752at2759; -.
DR Proteomes; UP000008141; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF97; METAL TRANSPORTER CNNM-5; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000008141};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 40..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..216
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT REGION 391..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 70170 MW; 7B6CE026B534E874 CRC64;
MVPLTHRLLL IGSVQAQSWL RHRGQAGSPA PLAEDDDEEM FVTYLLLSFF LVAMAGLMSG
LTLGLMSLDQ VDIEILHRSG TERQKRLAQR IRPMLKRPHV LLVTLLVCNA IAAEALPLVL
DRLADPVTAV IVSVTVVLLF GEIIPQAACS RYGLQIGAYS APFVRLLMML TAPISYPIGW
VLDQVLGHRH TALFRRAELK ALMDIHREGQ EFGGHLSAGK HTRQHGRTAA RLAGCQVPAT
PRHPPAVCHR RSAYEVSIIK GALDMTHKTA RDAMTPIDMV FMLPADDVLD EATLTAIMAS
GHSRIPVHRP GDRRAILGIM LVKELLLVDR SQGKTVGRQK VRSIPSVRAD TPLYDMLKLF
EIGRSHMAVL MQLKKKAAER RKQESEAELM HNIDSMSDDP SLESADEEQG LLSPRPTAQP
EDFIFDSAGS GAVSPVPSGG ARGATRTLRL PPSGRGGGQP PSAGASANNS THGGLLYKQG
SVGAALVAEA LRQEVALQLA AAAAAAAGGG VSRPSRSRSR SPLPTRGASR HSLSSPERAV
LWPPGSATVA PAGHVQPGSG GGGGGGGSAS GQQPLDVPPP LFPGLRRTRS ELANSSGAST
PRLVVPLPPP PARRSTNLSQ RVQEQMDLLE PLLITSRRAS GASSGVLSLE GEASGGATAG
SEG
//
