ID E2A0C5_CAMFO Unreviewed; 366 AA.
AC E2A0C5;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Spermine synthase {ECO:0000313|EMBL:EFN73128.1};
GN ORFNames=EAG_02055 {ECO:0000313|EMBL:EFN73128.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN73128.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867}.
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DR EMBL; GL435569; EFN73128.1; -; Genomic_DNA.
DR RefSeq; XP_011268744.1; XM_011270442.2.
DR AlphaFoldDB; E2A0C5; -.
DR STRING; 104421.E2A0C5; -.
DR EnsemblMetazoa; XM_011270442.3; XP_011268744.1; LOC105258881.
DR GeneID; 105258881; -.
DR InParanoid; E2A0C5; -.
DR OMA; YAGKEIC; -.
DR OrthoDB; 3059359at2759; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0016768; F:spermine synthase activity; IEA:InterPro.
DR GO; GO:0006597; P:spermine biosynthetic process; IEA:InterPro.
DR Gene3D; 2.30.140.10; Spermidine synthase, tetramerisation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR030373; PABS_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR035246; Spermidine_synt_N.
DR InterPro; IPR037163; Spermidine_synt_N_sf.
DR InterPro; IPR015576; Spermine_synthase_animal.
DR PANTHER; PTHR46315; SPERMINE SYNTHASE; 1.
DR PANTHER; PTHR46315:SF1; SPERMINE SYNTHASE; 1.
DR Pfam; PF17284; Spermine_synt_N; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01330; PABS_1; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Polyamine biosynthesis {ECO:0000256|PROSITE-ProRule:PRU00354};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 125..366
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 280
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 366 AA; 41305 MW; 5D650B6DD5A71E2F CRC64;
MVAHTVLLDF TVSSSVIADM EKRSGLKSAI GNVLAEHFIG LKPLTESNID GSLLVLYTGP
RGSLITVRGY TEGLITLNIE YYKQDDQEAL LTFEQLRYLE ADVAMALNSQ RSKHLPPIRR
GTIYDLYLTL SDERLLEYDI DKLVFEARSP YQKVQIVHSK SLGNLLVLDE LQNMSEADLI
YTETLMQRGK ENYAGKEIVI LGGGDGGLLW ELLKEKPKFV TMLEIDDIVM KACSQHMRSI
CGDCLDKRKG DNYEIIVGDC VKALAHMIEE GRQFDYVFGD LTDIPISTTP HGDAWDFIRL
ILNSSMKVLK PSGKYMTHGN GASCPESLKM YEEVLLQLCV PVTFTKDRAF VPSFFEDWIF
YQVSLK
//
