ID E2A4X1_CAMFO Unreviewed; 328 AA.
AC E2A4X1;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=TNF family profile domain-containing protein {ECO:0000259|Pfam:PF00229};
GN ORFNames=EAG_13702 {ECO:0000313|EMBL:EFN71513.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN71513.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the tumor necrosis factor family.
CC {ECO:0000256|ARBA:ARBA00008670}.
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DR EMBL; GL436756; EFN71513.1; -; Genomic_DNA.
DR AlphaFoldDB; E2A4X1; -.
DR STRING; 104421.E2A4X1; -.
DR InParanoid; E2A4X1; -.
DR OMA; INNIMSR; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR006052; TNF_dom.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15151:SF13; ECTODYSPLASIN-A; 1.
DR PANTHER; PTHR15151; PROTEIN EIGER; 1.
DR Pfam; PF00229; TNF; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000311}.
FT DOMAIN 216..303
FT /note="TNF family profile"
FT /evidence="ECO:0000259|Pfam:PF00229"
FT REGION 118..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 328 AA; 37674 MW; BDEE83E97D0031A8 CRC64;
MGTSILKNRM KHVGVYYCGA FGSCQTINNI MSRLRYNPIV YNARPWDIRS INDPFNLKPT
NVSNIENDQN SNTVLIIFDK DNSTVLSTSV QPVDHQDDAR KSRILDDINQ IMSEIKESKM
KDERDLSRKK RDIEIEAQNH TTTEDERNGN NTVDVQRKSR RLQRQLENIG RDPAVVTFVG
AIPEQDFQNT AYVGPWIKSN KDNGSYDFNK FYLAEENYSI EVTISGLYMI SVQIFYFGKS
TSHSYWVVLN SEGSSMKQKL ITCASASVSS SEISCYTGLT TYLRKGDRLS IQQQERNRFV
NLREGYSQVQ LVLLSNDKNR KRPNNKDL
//
