ID E2A5Q3_CAMFO Unreviewed; 493 AA.
AC E2A5Q3;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Major facilitator superfamily domain-containing protein 8 {ECO:0000313|EMBL:EFN71250.1};
GN ORFNames=EAG_13357 {ECO:0000313|EMBL:EFN71250.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN71250.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL437023; EFN71250.1; -; Genomic_DNA.
DR AlphaFoldDB; E2A5Q3; -.
DR STRING; 104421.E2A5Q3; -.
DR EnsemblMetazoa; XM_025409225.1; XP_025265010.1; LOC105248747.
DR InParanoid; E2A5Q3; -.
DR OMA; DQFAWSK; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17326; MFS_MFSD8; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR PANTHER; PTHR23510:SF3; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF07690; MFS_1; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..493
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003156946"
FT TRANSMEM 33..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..443
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 493 AA; 54451 MW; CE83BBC40624FA9C CRC64;
MFLMSLGFSI ILTGVWPYLD KLDPTAGKEF MGYVVAANPL GQMLFSPLVG WWGNKRGSVR
LPLLITLALF TIASAAYSIL EVIPGDKKSY MVVARFFVGV SSANIAVARS YLSAATKLSE
RTHAVSMVSL AQVLGFVVGP ALQAAVTPLG DHGIILMMLP INMYTASGWI NAIMGIFNFI
LFLPWNFKEY KIAIKEAMRN EGKATEKETW KAIKPDYLAS WTLICAFFVL VFNFVLLETL
GTSLTMDQFA WSKKEALYYM GILMSIGAII ACVTFTMIGP LCKKFEERKV MLWGGFFFML
IGRVLCIPLG SNPPQIADFG PNNNITVDVN GTEILGCPIT QEWCLYTPQL TITQFFIGYG
FTSIGYPLGV TLIQTIFSKI LGPRPQGVWM GLMTGAGCAS RVLGPVFVGL IYTRWGTYHT
FGITGAMLLI SMLWLQFVSG RLISPEVEKK DEALNRQGKD VEIPLVHLRA DNTQTSRETV
KFNGMSDCDC DKV
//
