ID E2A7C0_CAMFO Unreviewed; 606 AA.
AC E2A7C0;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
GN ORFNames=EAG_03806 {ECO:0000313|EMBL:EFN70617.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN70617.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR EMBL; GL437329; EFN70617.1; -; Genomic_DNA.
DR AlphaFoldDB; E2A7C0; -.
DR STRING; 104421.E2A7C0; -.
DR EnsemblMetazoa; XM_011254525.3; XP_011252827.1; LOC105249220.
DR InParanoid; E2A7C0; -.
DR OMA; VQWMRDQ; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07792; FGGY_GK1-3_metazoa; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR042018; GK1-3_metazoa.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF40; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:EFN70617.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Transferase {ECO:0000256|RuleBase:RU003733};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 578..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..317
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 332..517
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 606 AA; 67536 MW; 16D4DFC9285C4412 CRC64;
MNGNEEGDAK SERGTPEGSF EDSNASLEME ESEMGRRTSI FKYYSYKNTD TMPNSIRKIG
PLVGVIDVGT RTVRFVVFNA KHVAEVASHQ IDIEHISLQE GWMEQDPKNI LMAVKTCVDN
VNHKLNILGM KIDEIVTVGI TNQRETTVIW DAITGEPLYN AIVWSDIRTD AIVDQIIAKF
PDQNKNHLKP LCGLPVSPYF SALKIRWLKD NLPSVKKAIH ERRCKVGTMD TWIVWNLTGG
IDGGLYITDV TNASRTMLMN IETLSWDPTL CRYFDIPMQM LPEIRSSSEI YGKISIPPLS
GIPISGILGN QQAALVGQNC LKKGQAKNTY RSGCFLLCNT GHTRVYSSHG LVTTVAYQLG
PKSPPVYALE GSVAVAGAAI KWLRDNMKLI KDVHESEHLA QSVFNTGDVY FVPAFTGLYA
PYWRKDARGI ICGLTAFTTK QHIIRASLEA VCFQTRDILE AMHKDCGFPL TKLNTDGKMS
TNNLLMQLQA DLCGTPVFRS TMPDMTALGV AMAAGHAEGI DVWNLEGEEV ETVPSDTFLP
TTTSEERDAR YKKWKMAVER SLGWAIVKKS NQMTDERYYI LASIPASCFM LSSFILLRLS
NYIANR
//
