ID E2AB86_CAMFO Unreviewed; 331 AA.
AC E2AB86;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha {ECO:0000256|ARBA:ARBA00040965};
DE EC=2.5.1.58 {ECO:0000256|ARBA:ARBA00012702};
DE EC=2.5.1.59 {ECO:0000256|ARBA:ARBA00012700};
DE AltName: Full=CAAX farnesyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043086};
DE AltName: Full=FTase-alpha {ECO:0000256|ARBA:ARBA00042436};
DE AltName: Full=Ras proteins prenyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00041392};
DE AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043219};
GN ORFNames=EAG_01102 {ECO:0000313|EMBL:EFN69362.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN69362.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC family. {ECO:0000256|ARBA:ARBA00006734}.
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DR EMBL; GL438234; EFN69362.1; -; Genomic_DNA.
DR RefSeq; XP_011254823.1; XM_011256521.2.
DR RefSeq; XP_019882856.1; XM_020027297.1.
DR AlphaFoldDB; E2AB86; -.
DR STRING; 104421.E2AB86; -.
DR EnsemblMetazoa; XM_011256521.3; XP_011254823.1; LOC105250428.
DR GeneID; 105250428; -.
DR KEGG; cfo:105250428; -.
DR InParanoid; E2AB86; -.
DR OMA; HRHTIID; -.
DR OrthoDB; 20949at2759; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR Gene3D; 1.25.40.120; Protein prenylyltransferase; 1.
DR InterPro; IPR002088; Prenyl_trans_a.
DR PANTHER; PTHR11129; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11129:SF1; PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA; 1.
DR Pfam; PF01239; PPTA; 5.
DR SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR PROSITE; PS51147; PFTA; 5.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:EFN69362.1}.
SQ SEQUENCE 331 AA; 39376 MW; 66B4CA6D70660907 CRC64;
MSDSSDDELN CGDDHEKTSW TLYKDRDEWS DVTPLPQDDG PHPVVAIAYS EKFKDAYDYF
RAILKSGEKS ERALALTEAC IWLNPANYTV WQYRREILKA LAKNLQEELK YTVRMIKYNS
KNYQVWHHRK VIVEWLQDPS EELAFIESVL CKDAKNYHAW QHRQWCIQTF NLYEYELEYV
EQLLNDDVRN NSAWNQRYFV ISNTTKFEQE VIDREIDFSL EKIELSKGNE SAWNYLRGIL
LHDSKGLGYN EKVRQKCEEM YKEGCRTNHL LACIIDICQE ISSDETPSSL FHINSAYELC
KDLSKKYDTI RWRYWNYVGN QLKTIKLKTE A
//
