ID E2ACH8_CAMFO Unreviewed; 944 AA.
AC E2ACH8;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=EAG_03666 {ECO:0000313|EMBL:EFN68864.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN68864.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL438525; EFN68864.1; -; Genomic_DNA.
DR AlphaFoldDB; E2ACH8; -.
DR STRING; 104421.E2ACH8; -.
DR InParanoid; E2ACH8; -.
DR OMA; NPPEVQW; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 2.60.40.1150; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF3; AP COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 2.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 714..824
FT /note="Clathrin adaptor alpha/beta/gamma-adaptin appendage
FT Ig-like subdomain"
FT /evidence="ECO:0000259|SMART:SM00809"
FT DOMAIN 833..943
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
FT REGION 606..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 612..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 944 AA; 104283 MW; F34AC942641E9C5B CRC64;
MTDSKYFTTT KKGEIFELKS ELNNEKKEKK KEAVKKVIAS MTVGKDVSAL FPDVVNCMQT
DNLELKKLVY LYLMNYAKSQ PDMAIMAVNT FVKIATTVTR LESLACPIFA QDCEDPNPLI
RALAVRTMGC IRVDKITEYL CEPLRKCLKD EDPYVRKTAA VCVAKLYDIN AALVEDQGFL
DQLKDLLSDS NPMVVANAVA ALSEINEASP SGQPLVEMNA QTINKLLTAL NECTEWGQVF
ILDSLANYSP KDDREAQSIC ERITPRLAHA NAAVVLSAVK VLMKLMEMLQ SESDFVGTLT
KKLAPPLVTL LSSEPEVQYV ALRNINLIVQ KRPDILKHEM KVFFVKYNDP IYVKLEKLDI
MIRLASQANI AQVLSELKEY ATEVDVDFVR KAVRAIGRCA IKVEPSAERC VSTLLDLIQT
KVNYVVQEAI VVIKDIFRKY PNKYESIIST LCENLDTLDE PEARASMIWI IGEYAERIDN
ADELLESFLE GFHDENTQVQ LQLLTAIVKL FLKRPTDTQE LVQQVLSLAT QDSDNPDLRD
RGFIYWRLLS TDPAAAKEVV LAEKPLISEE TDLLEPTLLD ELICHISSLA SVYHKPPTAF
VEGRAAGARK SLPARSNSNE DSRTNAQQPH AQVIPAQDSL IGDLLSMDIG GPQAAMATPT
PAPQAAGLGL DLLGGGLDGI LSNTDNTSAA PVVSQSTTGL LGDIFGFSQG PVSYISPKVN
WLPAEKGKGF DIWGTFTRKN GQISMDMTFT NKAMQPMGGF AIQLNKNSFG LSPAAPLQVP
APLNPGASVE TNVILSTVGA VQRMEPLNNL QVAIKNNIDV FYFACIVPMN VYFAEDGQLD
KRVFLSTWKD IPAQNEVQYT LNGVMLTADQ VVQKMQQNNV FTIAKRNVEG QDMLYQSLKL
TNNVWVLNEL KIQPGNPDVT LSLKSRSVEV APGVFQAYNA ILHS
//
