ID E2AE18_CAMFO Unreviewed; 851 AA.
AC E2AE18;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 22-FEB-2023, entry version 49.
DE SubName: Full=Regulator of G-protein signaling 7 {ECO:0000313|EMBL:EFN68251.1};
GN ORFNames=EAG_13162 {ECO:0000313|EMBL:EFN68251.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN68251.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
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DR EMBL; GL438827; EFN68251.1; -; Genomic_DNA.
DR AlphaFoldDB; E2AE18; -.
DR STRING; 104421.E2AE18; -.
DR InParanoid; E2AE18; -.
DR OMA; RSDQYRN; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR CDD; cd08705; RGS_R7-like; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR034483; RGS_Egl-10.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF5; REGULATOR OF G-PROTEIN SIGNALING 7-LIKE PROTEIN; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 35..111
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 312..428
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 446..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 731..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 743..768
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..825
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 851 AA; 95283 MW; EAFF095E8476198F CRC64;
MEASSNQQQK EKEPRIHRPY AFDKMEGLVR EMQDPESGVP VRSQKQFLTS IPSAFMGYDL
IEWLMERLAI EESVEAVHIA NQLCQYGYFF PVNDSKTLTV KDDSSLYRFQ TPYYWPWQHR
TPDNVEYAIY LAKRTLKNKQ RHALEDYEIE ALNSLRKNLQ NKWDIIQLQA EEQVRLSKER
KKGDKIVSDS QERAFWRVYR PPPGCLSSLE VVPVPTRFRP GLPRPPSRKR TLADLQREVD
LLRNSLIRTR IKVSTAIENL KSYFNTYVEY DPMFVQPQPS NPWITDDHTF WQLNSPLVEV
PTEKRVKRWA LSMEELMSDP TGLQEFTNYL RKEYSHENIR FWLAVKDLRH SFQAQIPDKV
NEIFREFLAP GAPCEINIDG KTMEKVHQEM KNPSRFTFDS AAEHVYTLLL KKDCYPRFIR
SDQYRNLLAA GVQPLQKKRF FGFGGQAKKK VSSTSTPTTS TLQHANIGSG GGGGGGGGRR
RGSDRSLSGS AHELTVCGVL RDVSSAPRVP HSHSQSNLTD IPYRDAGATE VAVRPMDDVC
PWESAPGPST EHGADAVPSG GTASADQARH VWDSGGHATI HTAEAARVSR KNSAQLDSCS
SSSDVSLAMI EVTERLRKST SLTHGTVGAA TSGPGTITRN YSTCSASGRI RLSEMSRASV
SSCNYPSPHQ SFEYSHVVVE KVEERSSLEK IVPEEETSTE SVVVKESQSS PKATAKAPLI
SISAIVGDLP SDNSTMENID EDASESCTAR DAGDIVEDRT RGETDSRADT GADVSPVAEE
EPATTEEPPD EVQVVPVWEP DAQQEDRPAT AQAAPREKRD NNVNEVCPWE DEENCRVDAP
YVKTYATLGY L
//
