ID E2AIH8_CAMFO Unreviewed; 1821 AA.
AC E2AIH8;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=ATP-dependent DNA helicase HEL308 {ECO:0000313|EMBL:EFN66768.1};
GN ORFNames=EAG_08039 {ECO:0000313|EMBL:EFN66768.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN66768.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
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DR EMBL; GL439791; EFN66768.1; -; Genomic_DNA.
DR STRING; 104421.E2AIH8; -.
DR InParanoid; E2AIH8; -.
DR OMA; HNMCQQF; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR CDD; cd18026; DEXHc_POLQ-like; 1.
DR CDD; cd08638; DNA_pol_A_theta; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.20; -; 1.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR046931; HTH_61.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048960; POLQ-like_helical.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF62; DNA POLYMERASE THETA; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF20470; HTH_61; 1.
DR Pfam; PF21099; POLQ_helical; 1.
DR PRINTS; PR00868; DNAPOLI.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EFN66768.1};
KW Hydrolase {ECO:0000313|EMBL:EFN66768.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311}.
FT DOMAIN 238..412
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 451..646
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 31..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1376..1404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1821 AA; 205936 MW; 7F7BC1A8FFA0BCF3 CRC64;
MQSFGDDTLF AHISIEKKCR LLREQNGDKV LQEESGSDVS KNVKQNLPVS KFANKDSDVD
ESKLSHSTHN AKETIKQSES DFVKYFEDSI LFPRINGRNN VSSASSTLKE NRILSSKTNR
SPCKNKGNIN AISSIKKHSS NIINNVKKCD KFSAQNLHKN GSHDDIYNTI SGSSVAVSSS
IDSTCDKEIS NIILSRALCT QDRCKLASWG LPPNILQKYT ARGVDCMFTW QMECLSNHQV
MQERKNLIYS APTSAGKTLV AEILLIKTIL ERRKKVIFIL PFVSVVREKM YYFKDLLSDI
GIRVEGFMGG SVPPGGFAAT HVAIATIEKA NSLVNRLMEE NDLSSLGAVI IDELHLLGDP
NRGYLLELLL TKLKYMTLRN DDINIQLIGM SATLPNLVLL AKWLNAELYK TEFRPIPLNE
YCKVETNIYD NKLNFVRKLE QLPELEKDVD NMLQLCIETI SAGHSVLIFC PTKKWCEKLA
EQIAAAFFKL GCKDTMLGEM LRKEINKELI QETLEQLKRS PSGLDNILKN TISFGIAFHH
AGLTMDERDI IEGAFRTGSL RVLIATSTLS SGVNLPARRV IIRSPLFGNN LLNTLTYKQM
IGRAGRMGKD SAGESILICK STERNAALSL LSATLDPIES CLNDSMLLIR ALLEAVASEV
LYTVKDLELY INCTLLSFNK QSDVQTFSNE AMRFLLDNEF LLLQTTERES RWIATPLGKA
CLAASIPPRE GLFLFEELQK ARRCFVLDTE LHVIYLVTPL SAGCQIGTVD WMMFHELWNT
MSESERRVGK LIGVEERFVV SAIRGVIKPG KSLNIHRRFY SALALHDLVK EVPLHAVCKK
YGCCRGVLQT LQQSAATYAG MVTQFCKQLG WDCMELLVSQ FQTRLQFGVC RELLDLLRLP
MLNGLRARSL YKEGITCVAD LAVANELNVE RALYKALPFE SEKEYEGEYA FEAEKRNKMR
TVFVTGRDGL TPQQAAVLLV QEARVLVQNE LGLDQLPWEQ KHNEQSLQIT YIEDVKDTSD
IKEQIQMELD VKDSKSTKME TSIVNNSKYE KSANNENKKN DNSKLDIFDE IESNMPDKKK
TIESNNQPLN EVILSSKISE DERVFLDISI PDIIANNELQ TSKEKKNSLT PDNSIKMKRS
SKDLEKLNLN INDIPNKKSK TYNYLNKIKN NTENLIDKNV KVSILDKDTK LSYSRSPSLF
DDSLNLDTQI CDLLEQNVMD IAHLELDSKM FASDLDLVTN TLQKSPDINN AHLQGQSDAK
NVNTALIQTR NSVLSWDDDS WNNSERLLKQ VVQADNNQNR KQETPKPKII NIVNTNVSIT
PKNIKTCTPK DKKSINKTDM KKRTAVIKEK VPIIKPKLPK IESPITNIIV YRNERRKSAE
SNKSDSDDII IGSQHFDSPF NDSKNRARIK LKKIRKMRSQ KLAEDTLTEV NNRLNSPIRA
ESSDIARNKT KQKAKPKLKE ILERNLLLAN CNTDSIIYNS EDETTLSLAS KTKIIETQSN
LIQPLLKLAQ TDSRVRGNSI TCTVTGRVSM HEPNLQNVPK DFSFADNNFV LSVRMAFVPA
LGNIMLSADY CQLELRLLTH FSQDSILCEI MRQPGDIFKS IAAKWNNVSE EEVTIEMRQR
TKQLCYGMIY GMGVKSLAEN LCISESEAQE FLESFMSTYP GIYKWLNNVL EEAHRDVYIT
TLLGRRRQFP DLKSTKSSTR AQAERQAVNT KVQGSAADIV KKAMISIEER IRCNFPDSAI
IFPEMNNTRK LRSNSRDMQQ RGGYLVLQLH DELLYEVNLA DLKEVAAIIR ESMENVCQLT
VPLPVKIRVG PAWGDLTDYQ F
//
