ID E2AKP7_CAMFO Unreviewed; 716 AA.
AC E2AKP7;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Rhophilin-2 {ECO:0000313|EMBL:EFN65987.1};
GN ORFNames=EAG_03120 {ECO:0000313|EMBL:EFN65987.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN65987.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SIMILARITY: Belongs to the RHPN family.
CC {ECO:0000256|ARBA:ARBA00010369}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL440368; EFN65987.1; -; Genomic_DNA.
DR RefSeq; XP_011259915.1; XM_011261613.2.
DR AlphaFoldDB; E2AKP7; -.
DR STRING; 104421.E2AKP7; -.
DR EnsemblMetazoa; XM_011261613.3; XP_011259915.1; LOC105253527.
DR GeneID; 105253527; -.
DR KEGG; cfo:105253527; -.
DR InParanoid; E2AKP7; -.
DR OMA; PPVHDYM; -.
DR OrthoDB; 24567at2759; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09244; BRO1_Rhophilin; 1.
DR CDD; cd11633; HR1_Rhophilin-1; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR004328; BRO1_dom.
DR InterPro; IPR038499; BRO1_sf.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR047138; RHPN1_2.
DR PANTHER; PTHR23031:SF15; LD12055P; 1.
DR PANTHER; PTHR23031; RHOPHILIN; 1.
DR Pfam; PF03097; BRO1; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM01041; BRO1; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51180; BRO1; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51860; REM_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311}.
FT DOMAIN 74..148
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 160..550
FT /note="BRO1"
FT /evidence="ECO:0000259|PROSITE:PS51180"
FT DOMAIN 564..643
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 18..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 125..152
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 25..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..682
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 716 AA; 80733 MW; 22DDF1F659817775 CRC64;
MLKWVHYCPL PRDRAITSSD AKMVSGETTR DEKDGRRAVD RRKDSGGTMR SARNAKLTTP
DAIMRRCFRF GGSDPRVATC RGKLQNKRSK LNQEINKELR LRAGAENLFK ATTNRKLKET
VALELSFVNS NLQLLKEQLA ELNSSVELYQ NVDGVEPIMP MIPLGLKETK DIDFQDPFKD
FILEHYSEDG ENYEEAIADL METRQATRTP TRDSAGIALL LRYYNQLYFI ERRFFPPDRS
LGIYFEWFDS LTGVPSCQRT VAFEKASILF NAGALYTQLA AKQDRLTARG LDQAVDAFLR
AAGTFRYIHE NFTNAPSMDL GPDMLEMLVQ LMLAQARECL FEKLELQSRD GRNIDVCLDL
AQEAAQVAAI YNDVHGLISR QPVRDYVPET WISLILVKRE HHLALAHKHL AVGLLDRPIV
EFRVETRCTL EHIQKSDGKT QLDIIVPRDD NERKILGKAH LREALVLHDE SQRLQRMCRD
LKGKQALARV LKKAQEATLD SYNKFGNEDD FRELLDPPDI IASTKFQLSI THPDFGQHGV
DDLFRSLGPV AIFSAKRHWT APRLVQLQRG PDGEGFGFSV RGDAPVIIAA VDHNSLADVG
GMKEGDFIVG IGDKDVKWAS HEQVVRMIKQ CGDFINLKLV TPMDRNYLKK PGKPNSHHDK
GSVSASSSSG VSSGQPSPAG SVTTAHVVRR LPWNPFKKSG AQRENRDLTF DNVILR
//
