ID E2AZ20_CAMFO Unreviewed; 797 AA.
AC E2AZ20;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Protein enabled {ECO:0000313|EMBL:EFN61315.1};
GN ORFNames=EAG_00946 {ECO:0000313|EMBL:EFN61315.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN61315.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the Ena/VASP family.
CC {ECO:0000256|ARBA:ARBA00009785}.
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DR EMBL; GL444070; EFN61315.1; -; Genomic_DNA.
DR AlphaFoldDB; E2AZ20; -.
DR STRING; 104421.E2AZ20; -.
DR InParanoid; E2AZ20; -.
DR OMA; YQQMVQV; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
DR CDD; cd01207; EVH1_Ena_VASP-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR038023; VASP_sf.
DR InterPro; IPR014885; VASP_tetra.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR11202:SF22; PROTEIN ENABLED; 1.
DR PANTHER; PTHR11202; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF08776; VASP_tetra; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF118370; Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain; 1.
DR PROSITE; PS50229; WH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW SH3-binding {ECO:0000256|ARBA:ARBA00023036}.
FT DOMAIN 1..98
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT REGION 133..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 541..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..328
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..573
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..684
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 797 AA; 83814 MW; 63307BECD4B154F5 CRC64;
MVYDDVNKKW IPSGSSSGLS KVQLYHHQVN NTFRVVGRKL QDHEIVINCA ILKGLKYNQA
TVTFHQWRDN KQVYGLNFSS KDDADAFARA MLQALDVLSN GSNISRSLAP TTATTTQQQT
AYQQQQQQQQ QQQSQATAQY EEDMGYSESH TSVLTGCSQG RSARISLSLG HLPTGGQTAL
LVGTAITTPE HPNNATVSGA VGTVIQMGCA RGSPGDGHTR TMTREDVAII QERRMSQQSQ
ATGSPNPISP SCPPTAQQQQ QQQQQQQQQS GHHRTSSAPP APQPPQQQQS ALMQGVVMAP
APPQMSTGPP VPPPQPPIAP PAPPCPPAMM NFNSSAAPTP PMMMTQYAQS PSSQSNLANQ
QPQAIYVTNQ ASQYGAVPTS NQYAASAASA GGTGSTGASN VVGQSPNQYP QSSNPSNFYG
TNSQTSNYAT GGQTNAGQYN QSTGNQAAPY GTGGNQYGSS SSINQYAAGP PPPGPGSQYA
VAQPGQSQYG SIVSQAQAQY GGAASPAVPV AGATNPYGTP SNSVNQYAAA GLHTVAANAY
APIASSGPPP PPMIPLTGIA APPPPPPPPV PNANNSTASA SSVSSSSDPP PDTNSLAAAL
QARLKKKQQQ SQPVENSGSS TSSSGSGSSG NYGTLGRGGG GGMASMMDEM AKTLARRRAA
AEKKQPEQPP EPESSPDKKS WDKNNTSNNK FSNGAESPKS VRKRFGSASE DTLLKVNGVN
DGTSFTAQEM EAFKVEIIKE VRKEFQKMKQ EIIDGTDILL LQSLRKNLVA LIRILVDSTS
MFVGKWKNQN SCRRYIR
//
