ID E2AZ34_CAMFO Unreviewed; 5256 AA.
AC E2AZ34;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 03-MAY-2023, entry version 45.
DE SubName: Full=Protein purity of essence {ECO:0000313|EMBL:EFN61308.1};
GN ORFNames=EAG_10269 {ECO:0000313|EMBL:EFN61308.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421 {ECO:0000313|Proteomes:UP000000311};
RN [1] {ECO:0000313|EMBL:EFN61308.1, ECO:0000313|Proteomes:UP000000311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C129 {ECO:0000313|Proteomes:UP000000311};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SIMILARITY: Belongs to the UBR4 family.
CC {ECO:0000256|ARBA:ARBA00009970}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL444078; EFN61308.1; -; Genomic_DNA.
DR STRING; 104421.E2AZ34; -.
DR InParanoid; E2AZ34; -.
DR OMA; VHRMEEH; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19680; UBR-box_UBR4; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR025704; E3_Ub_ligase_UBR4_C.
DR InterPro; IPR045841; E3_UBR4_N.
DR InterPro; IPR045189; UBR4-like.
DR InterPro; IPR047509; UBR4-like_UBR-box.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR003126; Znf_UBR.
DR PANTHER; PTHR21725; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR PANTHER; PTHR21725:SF1; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR Pfam; PF13764; E3_UbLigase_R4; 1.
DR Pfam; PF19423; E3_UBR4_N; 3.
DR Pfam; PF02207; zf-UBR; 1.
DR SMART; SM00396; ZnF_UBR1; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51157; ZF_UBR; 1.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000311};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1696..1769
FT /note="UBR-type"
FT /evidence="ECO:0000259|PROSITE:PS51157"
FT ZN_FING 1696..1769
FT /note="UBR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00508"
FT REGION 597..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1474..1526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1656..1691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1767..1791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1805..1827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2775..2802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2941..3063
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3434..3460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3908..3927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1494..1522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1656..1674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1677..1691
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1809..1825
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2778..2800
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2941..3010
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3027..3050
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5256 AA; 584677 MW; 587FEEAB91513972 CRC64;
MAAKSGGHDE WLSVMKPILA TSPRSFNKND IIDLVKSIVK SENKFVSHED QYDIFYTAVA
ALSADCISGC ANTFAKSQIS IICQACKVLL AYLVDKLPQQ QTQTDVAPVL TTKQLLLPIR
ALCTGQSLLT SAEEIALISV IKNSKVPPHV TVLPGGKEKE SSQQSSVKES VRSRCDLSTS
ILEQLTMPLQ DFSSSSILAN EVSADSTSKN INAATNETHS DTKMIFVANN ISTLQNMGAG
DTLLDMCLNL PHLSRYTRKY QAYLSKKGFS LPANASEAHT IRHSLHSVVS DINIVHNVIS
LPILEPLTPQ KLEKLSLLTM SCLYCSIANA TASSIVGITN AVSPKCSTNT ATSNQANQNA
KTTDEEYDTL AITVVEKSLE IFGQVSNVIK NSTRAGGHIL QNHLLIGVWL LVAGLQAQLT
VSSFSAADKG KEEKGKSPSK ARDGGGRVNL MKVQQGFGVL SVALASHALN LMSALLEDVS
IEANSDVVAA VPEPAPLDIL STATALQRAV TFLQAVPLNH LLFYLATISY RKACTLKRVQ
KHPLEGDALS QSDSTTYYED LLSCSENSTD EEQTVMSVEE DSEPILGLWF EETLAPSDET
STNTNKETNN EASAERTTAT TIVPDNREPH GYISLATKIF QFMNKHLIGS RSTYVREYVV
NGLVEQQMVI LAAIIRDLDH ETARTETGTI SAFYGATLGA MYSDFSQALS RYTHNLLAWN
TLSESLQNIL LQHLGVNPWS VEVFNSSTTW PLQVYPRTLS VLAQVLLLKP QLEREAACIS
IWHRLVTTMV ENVCNPQTTY EAENEDLNVE HAQLVLFLFH SLNLMQKKSV LLVTGSGAVQ
WNLFSATSLV CDTKDGNKQT ARAFTPWVEI EDNYRKYGSQ DEFSMKPRFY NLSRTDFNNQ
DAPKLDGLAC NFILGTPDKM KYPLLVDALI DILNVLNQTD MHRKSSAENK EKITFTGLCA
IQYCFSICWE LLLMLPPSTP YMNKLALGEE IPAGPMLLHS LIWGPRAAYK TFTGWMKDCL
VKQGMYTQYA ENLLKTVSST VNSLKYDVTL AKNCIVSLKP EYNATDKIMP RASLPKLGSL
CILAAVVGKL QVLMDESISK NSAENIETSK STQNTDSAPS NRNKMIIEIL PHILSLTDAI
LLSCRSNILY HTFESTEEDG KYGIRDYLIL DNILSMAGAN WGTESSLVSF LPSCIKSALD
KWKSIAFAPV PWNTYANDII PAESYIFTTV NYHVSSLSEH PTFSINPSLK NLLYCLVSFM
MEYITSATVP EQQSDIHSQA VDILVSLSMD ARTDYLREMA TNTLAKLLGQ DNDNEARLLR
EHLFVLNHTY NLIIEYTDNA DGSISIVIDE EILKQCIKYW ERLLEKPLGC KALDLFFAPD
TSHSLVSILL SITSPQASPQ FSTYILHFFN ALFRTTEKTT NDGSLDRLCN SVANFANVES
EKLQTWLRHV ILGATNVPTS VSATNIPTST AGATNTLVTV SGTSEDGQKS DERNNASNNE
QTQWAISEGS GSNQPAVSND EQHSNHENSR FLRALTNYIV KDKSNVSTNV SITILQALIP
LAYHILSPTI EGNRFSELMH IMSTLADAGA EKGHTLLFKA TTEWVELCKE QIMNKDPQTF
DKPSSPYIEA GCCMLNYIAD IVGAICPQQA LSQDRATSPP WEGAVPNNSD LNDSDWVDEI
PHEDDDSAVE DSDEDSLCNK LCTFTITQKE FMNQHWYHCH TCNMVDGVGV CTVCARVCHR
GHDVTYAKYG NFFCDCGAKD DGSCQALTKR SPQSSEHQTT SNIPYSNVGA PTESNLLLTS
SLRRRASSPV HNSYDKHERS GRDTQRQVYL SKQLESSKDW IYSQLCKSGL VSSLVDLTRA
LVPAVDASCQ RYSPVGCHAR AQLALKHLHS LDKKYEHTDQ LMLPTLGSQE GAFENVRMNY
SGDQGQTIRQ LLSAHMIRRV AMCCLSSPHG KRQHLAVSHE KGKITVLQLS ALLKQADSSK
RKLTLTRLAS APVPFTVLSV TGNQWNEDFL AVCGFKDCHV LTFNSSGTVS DHLVLHPQLE
SGNFIIKALW LPGAQTQLAL VTADFVKIYD LGKDALSPQY YFLVPTGKIR DCTFMHAEDG
TFHMLLMSSA GYIYSQVMDE ESQAKHGAFY VTNTLDVYHP EIKDNGQVGG GGVSIYYSHA
LQLLFFSYAC GKSFIAPLKH MDSDITVVFQ INLASNKTNG NKSNNNQPQP LCQWSEVANH
PGLVCSILQT SNNPVILMIK PDTIMIQEIK IVPAKAKIMD MVAIRHPSSN AEHRTTLILL
CEDGSLRIYM ASMEQTGFWM SSTVQPISTN SGIKPARKKK ANKMGKPSGS ITFPIDFFEH
CQVMNDVEFG GNDLLQIYNV AQIKHRLNTT GMYVVSTKAM GFNVEVTNND AILVMTGIRV
LFGNQDIQRA PLSIRTTLTR SRWFDIPLTR EESLQADKKL TITFGPSQDP EGVIMVDSIK
IYGKTKDAFG WPEEIEEIQS CQPTSAPITT INNEADNTIV SPAPLSSLDK MTKDSSVNIE
RMIASVLEVL ESSFILSSHD DNKSSLKATA IDVASRLLIL PTPPSVQMHT TALLAALHST
KQAYHFHKDH ALLSHVLESL KSMREANDPA DIDAENFYRL VLIVRAIAVS RPHNLAKFAE
QYANKSIDES SVPVFEKDRL EARSCTKADG NQHLVIQLME ILWSLHTAYP KNMALAPVVV
PGLTHAEGTV HAIVEIVHAF AICDVENNTP IAAKLYLQLL LSSDTTISFS AKHAIIRVLR
PRYRRRRVYI PSPPNCSTPG VVAETEEKST SAPSQASQDA VERDVEQHFD IEAVEAVDRV
VDMLGAAESN QNSAAARVVN HHPLEALLGA GNFPQLLDVP PDADDEAMVE LAIALSLQDH
EGGHADLQAL RQGFQQSFPN LQGIQSLQNL SGSALQSLQN LAAQGLVQVP NVAQNQEAGH
YSDTTASAGG SDDEGSTAAT DGSTLRTSPA EQGGSGGSKG SESGGSDSGG SAVDSMTGEH
NVSGRSSAYG DNAPDNAMPP IGIGVNQAPR SETNTLDVPT TFTTTEQEEG TEQEQGVEQE
SDTTGEITIK LHAIRLSLLD RFTQFVPNLI NVRGVLAIPF MQVVLMLTAD LDGQDERDKA
CVERLLQMLV KELEMDKPDT SNICERSNKR EVHLVIMRLL SVLMSRSKYA TKTSSDNPNF
VSQTTAAILS KAGIIDYCLT LLQALLDYWK TTNTDESGTM IGGQLLKEHL TASPPDMSPF
FLRQYVKGHA GDVFEPYPQL LTEMVLRLPY QVHKYAESTV VQPAFEQPWY FYLCEYMMSY
QTPFVRRQVR KLLLFICGNK EKYRQLRDLH ALISHVQSVQ QCCTTGGYDP SHTRPHSINL
PYDSLVELIE HLKCCVEIAT SRTGNWQRFC LKQNTVLSYL FAISTLLDEG VSPTVLQLLQ
CAICSNNKSK ETKDTKIKES KSTTGTKERR EREKSEDSDT EAKFEEAQCL TLVEQIQKQV
HPTLLMKFIQ TFLLETNNTN VRWQAHSLIL AIYKNCGPTD QEVLLDLLWR LWPLLPAYGR
KAAQFVDLLG YFCLKTPHAG KKMHTYMEQA VAVLHAQNQL LARHPNANLY VNLAQFVELD
GYYLESEPCL VCNNPEVPMA TIKLSSIKVD SKFTTTTQIV KLVGSHTISR ITLRIGDLKR
TKMVRTINVY YNNRSVQAVV ELKNKPAMWH KAKKITLAQG QTEVKMEFPL PIVACNLMIE
YADFYENIQA SSETLQCPRC SASVPANPGI CANCGENVFQ CHKCRAINYD EKDPFLCHAC
GFCKYAKFDY TLTGRPCCAV DPIENDDDRK KTVATINTLL EKADRVYKTL ISNKPTLEML
LVKISEHRLD RGLEDGIQVS GSTQVNRAIQ LLAQRYCGEC KTSFEELSKI IQRVLACRRE
LVAYDRNQRG GQSSSQSSSY GTSSMNDSVT KDETIVLPVG RCYGCASAAT EHCLTLLRAL
ATNSVARDVL CKQGLIQELV EHNLRKGTVQ MQEEVRQLLC LVTRDNAQST KEICSLLTSR
ITLTLRGRVA TPDLSVAVRH EMALLAALVQ KEDSCWEQKL RCVMQLFLTA CKESKSPVVM
ESIILPCLKI LQGLIKPDQP VSKKNKDKTI ESLATVQPPE GISIDVSKWI TGDPKHSYSE
WLRRMPAKKT EPSTTAKSLK KEETRVLYLM EKYGHRWHQR CLRHQGVQPL KLSDGAWLKE
VLFNPSSRLA RQVACNMIES LCQGTERKKE VLVLLTCYLE ELRTAGESST EFLTLYQSLI
RQSPWKQFLA VRGVMTLLAD LLTREIEELH RLEETTLTSD LAQGYSLKML TELLATFLEQ
ENIKQQYKGR LVGAVLNGYL SLRRLVVQRT RLIDDTQEKL LELLEEMTTG TEEETKAFMA
ICVETIQKQN PQDVRTPVFI FERLCSIIYP EENDIGEFFL TLEKDPQQED FLQGRMLGNP
YSSLEPGLGP LMRDVKNKIC QDCELVALLE DDNGMELLVN NKIISLDLPV KEIYKKIWVL
EGGECDAMRV VYRMRGLLGD ATEEFVETLN ANSEQEVNNE EVYKMANVLA DCGGLQVMLD
RLAAIHDVNR ARPLLQVLLK LFRLCVKVKK NQEVLSKPEL KAVTVFLDVL QRCLATESEN
SQAKITEQLL DIMETILANA ASQPFSAFEA FSRTLGGPEH IKALLSCTQS TAVRQSAGVL
AHLARVLAAL TYGNKEKMAL LCDYFKPVLN FYKFDFEHTP EDEQKLELFC ILTQGIERNA
IGNTLKDYII SMGIVKDAFE YITVHAPCVK PTLLRTDSDE LKEFISKPAL KYILRFLTGL
ATDHEPTQLT VSQVTISIIH RLEQVSSNEH VGSLAENLLE ALCTNKQVAE LIEEARQHTR
SEKKRLAMAM RERQLGALGM QTNDKGQVTA SGTILQQMED LGDETGLVCV ICREGYKFKP
NMVLGVYTFT KRCNVEEFET KQRKTVGYTT VTHFNVVHVD CHMSAVRLAR ARDEWESAAL
QNANTKCNGL LPLWGPQVPE SAFASCLARH NTYLQECTSH RDISYSSTVH DLKLLLLRFA
QEKSFHEDTG GGGPQSNMHI VPYLIHMALY VVNTTRSGAR EDKALMTYLE VPPGSAWLDN
SYEAEGPLYQ CVLSLLFFTP ARWKSHRLTH LNRLLILAHQ RYVSPSATTK TIMEPTAKDY
AVYKSTLVFF GLVDCIYGNF FKKVNVLSDD QWPSVLAEYI RHNDEAMLKA SERVLSSYRD
ELLPCASFEE FCDIVGLLED IRNPSTYIDD ILRRLA
//
