ID   E2B387_HARSA            Unreviewed;       511 AA.
AC   E2B387;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Sorting nexin-2 {ECO:0000313|EMBL:EFN89869.1};
GN   ORFNames=EAI_15082 {ECO:0000313|EMBL:EFN89869.1};
OS   Harpegnathos saltator (Jerdon's jumping ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX   NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN   [1] {ECO:0000313|EMBL:EFN89869.1, ECO:0000313|Proteomes:UP000008237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN89869.1,
RC   ECO:0000313|Proteomes:UP000008237};
RX   PubMed=20798317; DOI=10.1126/science.1192428;
RA   Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA   Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA   Wang J., Liebig J.;
RT   "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT   saltator.";
RL   Science 329:1068-1071(2010).
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   EMBL; GL445305; EFN89869.1; -; Genomic_DNA.
DR   RefSeq; XP_011135813.1; XM_011137511.2.
DR   AlphaFoldDB; E2B387; -.
DR   STRING; 610380.E2B387; -.
DR   EnsemblMetazoa; XM_011137511.3; XP_011135813.1; LOC105181034.
DR   GeneID; 105181034; -.
DR   KEGG; hst:105181034; -.
DR   InParanoid; E2B387; -.
DR   OMA; YWESFLP; -.
DR   OrthoDB; 1891044at2759; -.
DR   Proteomes; UP000008237; Unassembled WGS sequence.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd07623; BAR_SNX1_2; 1.
DR   CDD; cd06859; PX_SNX1_2_like; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR015404; Vps5_C.
DR   PANTHER; PTHR10555:SF170; FI18122P1; 1.
DR   PANTHER; PTHR10555; SORTING NEXIN; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008237}.
FT   DOMAIN          126..259
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   511 AA;  57633 MW;  43BA8EBC0550816B CRC64;
     MADMTESPPL FDTNETKLDD LEDDDEDIFA SAVQEQNQLE NSSPYNGVPK IQAELPKLSL
     RDAPEDNSFS SVSSPVPGPL SPPLGPMNTD IGDLHDVPIN DNADMLSSSV MQSRSLEEVP
     TDTSEVFLKI TVTSPQKIGD GMGAYVAYKV ETRTNMLIFK KRHFSVIRRF SDFLGLHDKL
     TEKYLRNGRI IPPAPEKSVI GTTKIKMSGD KSQEQNSSST EFIERRRAAL ERYLNRTAAH
     PVLSIDPDFR EFLEADVELP KATNTSALSG KGVMRLFNKV GETVNKITYK MDESDMWFEE
     KTSQIDSLDI QLRALHSAVD SLTNQRRELA NCTGATAKSI AVLGHGEPGA SLGRALAQLA
     ETLEKVEAIR KTQSNSDLYQ LGEMLRDYVA LIGAIKDVFH ERVKVFQNWQ HAQLMLNKKR
     EQKARLEQSG RTDKTSQAAT EVIEWEAKVD RGQEEFDNIS KMIKEEVERF ELVRVQDFKK
     QLIEYLESML QHQNLLIKYW ESFLPEARAV A
//