ID   E2B3A5_HARSA            Unreviewed;      1327 AA.
AC   E2B3A5;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=SOSS complex subunit A homolog {ECO:0000256|ARBA:ARBA00032741};
GN   ORFNames=EAI_13970 {ECO:0000313|EMBL:EFN89783.1};
OS   Harpegnathos saltator (Jerdon's jumping ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX   NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN   [1] {ECO:0000313|EMBL:EFN89783.1, ECO:0000313|Proteomes:UP000008237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN89783.1,
RC   ECO:0000313|Proteomes:UP000008237};
RX   PubMed=20798317; DOI=10.1126/science.1192428;
RA   Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA   Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA   Wang J., Liebig J.;
RT   "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT   saltator.";
RL   Science 329:1068-1071(2010).
CC   -!- SIMILARITY: Belongs to the Integrator subunit 3 family.
CC       {ECO:0000256|ARBA:ARBA00006130}.
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DR   EMBL; GL445323; EFN89783.1; -; Genomic_DNA.
DR   STRING; 610380.E2B3A5; -.
DR   InParanoid; E2B3A5; -.
DR   OMA; DWLFYDP; -.
DR   Proteomes; UP000008237; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR045334; INTS3.
DR   InterPro; IPR019333; INTS3_N.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR13587; INTEGRATOR COMPLEX SUBUNIT 3; 1.
DR   PANTHER; PTHR13587:SF7; INTEGRATOR COMPLEX SUBUNIT 3; 1.
DR   Pfam; PF10189; Ints3_N; 1.
DR   Pfam; PF13414; TPR_11; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50005; TPR; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        133..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        161..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REPEAT          8..41
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          76..109
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   DOMAIN          311..717
FT                   /note="Integrator complex subunit 3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10189"
FT   REGION          213..234
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1163..1188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1242..1327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..231
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1163..1185
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1276..1291
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1298..1327
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1327 AA;  151658 MW;  44B0955339630692 CRC64;
     MNAREAEVDN LKQQGNACVK EQKYEKAMFH YTHAIKLDPQ NYSLYSNRSF AFLMMRQYHY
     AMEDALMTIQ LKPDWSKGYF RKGEVELRTF RFNDALQSYN KALSLQPSES RILEAMNKAS
     KSLIKDKRAD QQIPWLGAGV GIILGVIVVI ADYVFTNKPT LTHPLLMALL TMSISMLGFG
     IAKGFRYFVK CQRRNLLEPP VDLFPEEKED YENIDTERSN EKEKHPKGTG LRAEGSTEPC
     IAFTSRLWRS QRAMEQPKTL ASRLLNTTCI ENKDDLEEKF ERCYTVLQNL TTGLSEKEAH
     DTLNNAVCKD KTHEEVSLGL LVVILTDPQN AAKSYRDLTL ITRDGLSIVL IHLNQLVLER
     YLRLNDITRS QVLWLLREMI RTSVTNVDTL CLTLLRHAAG GDISPKNLYL VDALLDIFQE
     NRSWLDKFPF VVASVVYTYL RLIEDHNASH LAGLRQKEVS FTVTLIRERM VDCLAIGRDF
     VRLLQNVARI SEFEALWKDI LQNSKCLCSN FNGVLQLLQT RTSRRFLQSR LTPDMERKLV
     FLTSQVRFGN HKRYQDWFQR QYLATPESQS LRCDLIRFIV GVIHPTNELL CSDIIPRWAV
     IGWLFTTCTS TVAASNAKLA LFYDWLFFEP DKDNIMNIEP AILVMHNSMR SHPPVTATLL
     DFLCRIIPNF YPPLTDKVRN GIFSSLRQIL EKRVLPSLYP LFDSPKLDRE LRSKIRETFK
     EFCLPPNADP GKMEELNKEH NPTAVIENIA NSTVENNHVT QDPEPAFSDE EEESPLRIVT
     KVEEEEDEED VPLSTVKLKN EQKNANCVMK KEDIVSQLNL ILEPEELKTS IEIMHTETDN
     EAKCQAMERI VQMVVEDEID AETIPALASC LSSILSSQIT TQIFPDNLNE ETLTDSISTP
     LFVMFRNQFQ LCKEEDNRRK LLARVLAEMQ SLQPRIGYLL LYFLKVWGRE EEKREGEPSN
     VLNDVKASVY KDFCAQREKK LDVCLVSDLK LCHEDNIFML CYLLPDVYTG FQNVAVGNAQ
     LLHLVVSTVD SCQLQDLICQ IMQGHLKMLK KESFTSLLTA SLNWDTFEQY CFWQLIFAHD
     FPIDYVLPVL PKLQFRNHAE ALTSILFMLK QEKPTPDLLR QLLARQSVDG DMFVVAVLRY
     WCRDYEEKLG ELLANLLSTR YPATSPNKRK RSGGKQNQQS GPPTGEQVLG HLDQLRQHCS
     SSSELQLYHS EGMQRALQQA QAASSDSLRK SYGDLFALAE VNEENEPPPP PASSSARKHA
     TASSGGGAGG KGGHRKTGAN TRERSNAKRP LPRYHVDTTS SSEEEEIVNP KQAKKRKKIN
     PVGSDSD
//