ID   E2B3D6_HARSA            Unreviewed;      1040 AA.
AC   E2B3D6;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Protein SMG5 {ECO:0000313|EMBL:EFN89814.1};
GN   ORFNames=EAI_14004 {ECO:0000313|EMBL:EFN89814.1};
OS   Harpegnathos saltator (Jerdon's jumping ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX   NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN   [1] {ECO:0000313|EMBL:EFN89814.1, ECO:0000313|Proteomes:UP000008237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN89814.1,
RC   ECO:0000313|Proteomes:UP000008237};
RX   PubMed=20798317; DOI=10.1126/science.1192428;
RA   Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA   Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA   Wang J., Liebig J.;
RT   "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT   saltator.";
RL   Science 329:1068-1071(2010).
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DR   EMBL; GL445323; EFN89814.1; -; Genomic_DNA.
DR   RefSeq; XP_011136500.1; XM_011138198.2.
DR   AlphaFoldDB; E2B3D6; -.
DR   STRING; 610380.E2B3D6; -.
DR   EnsemblMetazoa; XM_011138198.3; XP_011136500.1; LOC105181431.
DR   GeneID; 105181431; -.
DR   InParanoid; E2B3D6; -.
DR   OMA; CAMDGGT; -.
DR   OrthoDB; 1356823at2759; -.
DR   Proteomes; UP000008237; Unassembled WGS sequence.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
DR   CDD; cd09884; PIN_Smg5-like; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR018834; DNA/RNA-bd_Est1-type.
DR   InterPro; IPR019458; Est1-like_N.
DR   InterPro; IPR045153; Est1/Ebs1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR15696:SF0; PINC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR15696; SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7; 1.
DR   Pfam; PF10374; EST1; 1.
DR   Pfam; PF10373; EST1_DNA_bind; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   4: Predicted;
KW   Nonsense-mediated mRNA decay {ECO:0000256|ARBA:ARBA00023161};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008237}.
FT   DOMAIN          77..197
FT                   /note="Telomerase activating protein Est1-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10374"
FT   DOMAIN          206..406
FT                   /note="DNA/RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF10373"
FT   REGION          425..654
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        426..444
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        445..464
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        527..554
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        555..593
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        616..654
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1040 AA;  117468 MW;  418D88A7AA2E1C54 CRC64;
     MRRTCNAVVE ARTTDSLEAT RRLHRSVTEI VKRLDEQKNR ALTVCDIFIP SVEVLRVKLK
     DYCERLILKD PVGNARKTEE LLWRKAFYDV VYAAKKLRKT NQWNESEKAL LSVHLAVGVG
     YYHHLILRLQ SEYDLDLVGV IDFAFTRFES ISSYARWMAK MEQPKLTHTK EVKQCVMRLI
     HRSLVCLGDL TRYKLELDSD WDPMIANRYY KMAIAIDPNI GMPHNQLGTI AGGKNYGLDA
     VYHYMRCVLC PELFEGAEGN LKRSIITNST CTDENNLVHH CVSRLFSLLR LWDYDNPNSD
     KINQECQDLL TDIENCLIIE QSETNNTSSL ENADNIETYL QNCKSRPALY LTDDMVFKIV
     TICLMSISRL KSRESSEVQG VVAITLAILS QLLQFTITKL QALVMETAVP DVEVNANSYS
     SKLKNALKKE APRDEREDSV DHVPKENSVS NQDNNTSNLN KKEQSHAIEG AKSLDNGVTN
     NETSKKTREK SKSLLSKLRR RKRRTSSDSD ASDTEQPVLV SSSDEMHSET EEDDALSEEN
     DALSEDALSD DNTDDEELLS LRNKKQSDEN ATKKEINGHA DVADCKTEDS VNKDDNSQLV
     NGEQRVADEQ AEPKPISDQD SVTNSAGSAV TITTNPDSTS SAFEESSNSN SSNTVTCMAQ
     SKKQSLKSNS VLNLLIGKEI LASIKVCFDW LRSSPDIVRI CAKSSRILLK RVTILLNLIN
     VDGEAFLPKN EDSAILASAE RLRECVRTLP LPEDNDLKGL TLLEEAHRSL NWCILHKHKM
     SKREETLLRM LKLVEFGRHL SAIEESGVQY DPVERLFVAS DYSPSNAPKP VGLDEKKFNM
     EHPRNKLMRH MGKLWLKAEV RALESQLHFR LMSPYLVPDH EALAKYTPTL KRLVYAKIFV
     VVIPAAVVSA LDEVKRISGQ AREATRWLEI QLRRGTRFLR AQRPHERLAL PLIKGPRPKD
     KEAWLFFQII ECCHYLTQQA KAGFTGDGEA PVVTLLTGCN PDERKALTFS PDGLAKSAGV
     NLEHIESFQT KWKSSSKSHG
//