ID E2B559_HARSA Unreviewed; 413 AA.
AC E2B559;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Protein vav {ECO:0000313|EMBL:EFN89171.1};
GN ORFNames=EAI_12274 {ECO:0000313|EMBL:EFN89171.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN89171.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN89171.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
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DR EMBL; GL445722; EFN89171.1; -; Genomic_DNA.
DR AlphaFoldDB; E2B559; -.
DR STRING; 610380.E2B559; -.
DR EnsemblMetazoa; XM_025304599.1; XP_025160384.1; LOC105186536.
DR InParanoid; E2B559; -.
DR OMA; MHRDRTD; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd01223; PH_Vav; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR037832; PH_Vav.
DR PANTHER; PTHR45818; PROTEIN VAV; 1.
DR PANTHER; PTHR45818:SF3; PROTEIN VAV; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237}.
FT DOMAIN 57..235
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 268..373
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT COILED 147..174
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 413 AA; 48262 MW; D7D03EA6B8FC5D3A CRC64;
MRVAAGDLRD ERVMRRVEGG ITKILLLRRT GTERFAVTRK VRRSTRTFGG AITGGEKRDY
VIQELVETER NYSEVLSSLL RHFARPLSSL LRPEDNVRIF FGIKELSEIH VGFHSQLRKA
RSGAALAHVF LDWREKFLIY GDYCANLTLA QNTLQEACAR NEVLNQEVIR CQQEANNGKF
KLRDILSVPM QRVLKYHLLL DKLVEETPRE WVEDYRQLAK AREVMVDVAQ YINEVKRDSD
TLDIIKDIQA SIIDWDVPED TQLKDFGRLL RDGELKVKAH GDQRIKARYA FIFEQVVLIC
KAGRGDQYCY RETLRLDDYR LEDHIGRRTL GRDSRWSYQW LLVHKQAYTA YTLYARTEEQ
KQIWIKALQD AIDNVNPAAC RSTNHKFKLT TFDTPRSCHR CGRFLKGCIF QVK
//
