ID E2B7C1_HARSA Unreviewed; 752 AA.
AC E2B7C1;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=GDNF family receptor alpha-3 {ECO:0000313|EMBL:EFN88406.1};
DE Flags: Fragment;
GN ORFNames=EAI_01826 {ECO:0000313|EMBL:EFN88406.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN88406.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN88406.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SIMILARITY: Belongs to the GDNFR family.
CC {ECO:0000256|ARBA:ARBA00005961}.
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DR EMBL; GL446154; EFN88406.1; -; Genomic_DNA.
DR AlphaFoldDB; E2B7C1; -.
DR STRING; 610380.E2B7C1; -.
DR InParanoid; E2B7C1; -.
DR OMA; AGPTSEC; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR InterPro; IPR016017; GDNF/GAS1.
DR InterPro; IPR037193; GDNF_alpha.
DR InterPro; IPR003438; GDNF_rcpt.
DR PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR PANTHER; PTHR10269:SF12; GLIAL CELL LINE-DERIVED NEUROTROPHIC FAMILY RECEPTOR-LIKE, ISOFORM E; 1.
DR Pfam; PF02351; GDNF; 2.
DR SMART; SM00907; GDNF; 2.
DR SUPFAM; SSF110035; GDNF receptor-like; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:EFN88406.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 235..314
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT DOMAIN 326..407
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT REGION 81..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFN88406.1"
FT NON_TER 752
FT /evidence="ECO:0000313|EMBL:EFN88406.1"
SQ SEQUENCE 752 AA; 84783 MW; 396A9648C34CDF3A CRC64;
PHSPHSRPRL CFCVTEFLPS STSVDLSGTD SALYPFDPQQ ENYQEIWLPP TSMYPYFLFP
GTARTPPYYD PESTYDIREP GEQHRHRHGH RHHHGHQEAP ELPGRPAVLV VEAYDPRPDS
DRYDTDVNRM LGPTPKDRTF CQTCYAQSFT VKVIAHPDNS TSFEVIESQL ENPLIHVDRQ
DLLDMKQPPS PDGHHHRSHH KRNHTDDFEQ PVLPSSTSNI DRLQQPVKLV LSSTCHHAYT
SCKSDPECKN LLQPVLNHCD SATCARNECM EALQHFYRTA HHKHSVEIAF CLCRKTDGKK
DECIVAQEKM HPACAQRVDG AEMPTCHSLA EACKENKGCR LRLEYYEQSC AVDSVTKKCA
GPTTECRKAM LGILGTELRT NCACKGTEIN QLYECLGWQR LLWVNPCVVE SQKDYHARRK
HHHPRTTTTT TATATAVAST TRSPASTTAT TAVEQVEDNQ IPEVTRWPTT EPTETWEITT
TTISTTPSTT TTTTMPPRFC AVQKPRQSPQ YIREGKAKRL YREEEPECSE LCQCEESSLS
LICHTICVDM SPCKTDFAFY NHEAPAYQAH RGPCLCYSGG FICMRPAPDT YSIPHGVFMF
LGYSEKDETL LKQHNNLTVL DAVSSLDNFM KQEVNNQTVC TLFLYNATRE NVIAVARLGT
DNPPLNSSQA QSLQHLLRVK EECASMMQDL SDKINNKHHE VHTHPLLSIF KMAEVEVKMP
YSNEAAISRS RPGLLVVLLA LGLLGSSCLF GS
//
