ID   E2B8I1_HARSA            Unreviewed;       249 AA.
AC   E2B8I1;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Atrial natriuretic peptide receptor B {ECO:0000313|EMBL:EFN88015.1};
GN   ORFNames=EAI_11642 {ECO:0000313|EMBL:EFN88015.1};
OS   Harpegnathos saltator (Jerdon's jumping ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX   NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN   [1] {ECO:0000313|EMBL:EFN88015.1, ECO:0000313|Proteomes:UP000008237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN88015.1,
RC   ECO:0000313|Proteomes:UP000008237};
RX   PubMed=20798317; DOI=10.1126/science.1192428;
RA   Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA   Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA   Wang J., Liebig J.;
RT   "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT   saltator.";
RL   Science 329:1068-1071(2010).
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DR   EMBL; GL446332; EFN88015.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2B8I1; -.
DR   EnsemblMetazoa; XM_025303629.1; XP_025159414.1; LOC105192252.
DR   InParanoid; E2B8I1; -.
DR   Proteomes; UP000008237; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR11920:SF494; GUANYLATE CYCLASE; 1.
DR   PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000313|EMBL:EFN88015.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          2..41
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|Pfam:PF00211"
FT   REGION          61..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..249
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..85
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..138
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..217
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   249 AA;  26613 MW;  62A8FB5013654AF9 CRC64;
     MIHVSPKTKE ILDTFGTFDL VCRGEVTLKG KGTMTTYWLM GEKPINNNVQ QTNPTTTIGQ
     ISSSAQDQLA AGTQLSPTQP KQQEQRTPVV RHKHQAHSDL EVVSSGWPDA QQSIQSRNQE
     PPRLGHPGQQ RPQESQQLQA LTTQARSQAT QLSRRAGSES PILNQIQQQK AAANPACGLS
     VTGNGAPKSS VSPRGVATAS PLGSSSPSRN SASNHPMHQV YLEAESMPNH TESGSNAPLL
     LPAGAVPRV
//