ID E2BJ44_HARSA Unreviewed; 494 AA.
AC E2BJ44;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Fibroblast growth factor receptor substrate 2 {ECO:0000313|EMBL:EFN84194.1};
GN ORFNames=EAI_09982 {ECO:0000313|EMBL:EFN84194.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN84194.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN84194.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
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DR EMBL; GL448558; EFN84194.1; -; Genomic_DNA.
DR RefSeq; XP_011139801.1; XM_011141499.2.
DR AlphaFoldDB; E2BJ44; -.
DR STRING; 610380.E2BJ44; -.
DR EnsemblMetazoa; XM_011141499.3; XP_011139801.1; LOC105183409.
DR EnsemblMetazoa; XM_025303908.1; XP_025159693.1; LOC105183409.
DR GeneID; 105183409; -.
DR KEGG; hst:105183409; -.
DR InParanoid; E2BJ44; -.
DR OMA; DIILYQR; -.
DR OrthoDB; 2996885at2759; -.
DR PhylomeDB; E2BJ44; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01202; PTB_FRS2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR038742; FRS2_PTB.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR PANTHER; PTHR21258:SF55; FI23523P1; 1.
DR Pfam; PF02174; IRS; 1.
DR SMART; SM01244; IRS; 1.
DR SMART; SM00310; PTBI; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51064; IRS_PTB; 1.
PE 4: Predicted;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Receptor {ECO:0000313|EMBL:EFN84194.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237}.
FT DOMAIN 10..112
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
FT REGION 138..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 417..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 494 AA; 54032 MW; E2E964268F124874 CRC64;
MGCINSRADI NDLHPNVFQV INVDELGNSI TPGRLEVTEV ELILYQRGKQ PIKWSLRCLR
RYGYDASIFS FESGRRCFTG PAIYAFKCQR AQQLFNLVQR NIQMFNNSGD DSLSDLPLGY
HPAAPLTNTN RSCRVTIPEE PNYLDPTPTR SNRVGSRFTH SPQNGVGRLN SVGSSNSPMS
PQGTMGSPSP PPISIPPSIS QTHPSSLYIN EEVWSSIPVE VEHNNNKSLG NAMQRSLQLS
TTIDNSTTAD SGLMETELIS IQNNAEANGQ QDVASQSLPV APYVNIDICG DKNPITSTPN
ISEPTPAKEE NNDAAESESS SEHEYMNIGP GRECIENVVV RVPPPPLPVL PFLQTEADVE
DGSKHYYSNL DPSEIESLRN RYSGASVAEK SPLLPSTPTG CPIREVNYAV LDLDTKDVPT
TTDTSESTVN SMPPPPQSPS KLQKGYATID FNKTAALLNS TNLVNDNEGS RKTRHNSTIS
DLTVQYRHNS SVSE
//
