ID E2BJ57_HARSA Unreviewed; 503 AA.
AC E2BJ57;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Thiamine transporter 2 {ECO:0000313|EMBL:EFN84207.1};
GN ORFNames=EAI_09995 {ECO:0000313|EMBL:EFN84207.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN84207.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN84207.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|PIRNR:PIRNR028739}; Multi-
CC pass membrane protein {ECO:0000256|PIRNR:PIRNR028739}.
CC -!- SIMILARITY: Belongs to the reduced folate carrier (RFC) transporter (TC
CC 2.A.48) family. {ECO:0000256|ARBA:ARBA00005773,
CC ECO:0000256|PIRNR:PIRNR028739}.
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DR EMBL; GL448558; EFN84207.1; -; Genomic_DNA.
DR RefSeq; XP_011139817.1; XM_011141515.2.
DR RefSeq; XP_011139818.1; XM_011141516.2.
DR AlphaFoldDB; E2BJ57; -.
DR STRING; 610380.E2BJ57; -.
DR EnsemblMetazoa; XM_011141515.3; XP_011139817.1; LOC105183421.
DR EnsemblMetazoa; XM_011141516.3; XP_011139818.1; LOC105183421.
DR GeneID; 105183421; -.
DR KEGG; hst:105183421; -.
DR InParanoid; E2BJ57; -.
DR OMA; VKPIEPF; -.
DR OrthoDB; 51626at2759; -.
DR PhylomeDB; E2BJ57; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0090482; F:vitamin transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002666; Folate_carrier.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10686; FOLATE TRANSPORTER; 1.
DR PANTHER; PTHR10686:SF18; FOLATE-LIKE TRANSPORTER 3; 1.
DR Pfam; PF01770; Folate_carrier; 1.
DR PIRSF; PIRSF028739; Folate_carrier; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR028739, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|PIRNR:PIRNR028739}.
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 503 AA; 57366 MW; 5A16075FC212CE7D CRC64;
MHWIRISCIL CMFGCFKDFR PSESFVTNYL MGPWKNFTSS EVNQDIYPVS TYCYAAMLIF
VFLITDFVRY KPIIILCGLS GVTTFVMIVL GQTVLVMQIM EFFYGLFLSA EVAYYTYIYA
KVDKKHYQEV TGHTKAASLF GRSMSGVVAQ LTASFNILDY HQLNYVTIAA FSTATIWALF
LPSVGQSIYF HRASTCDEEN SIGEQEKKEV AQSRQRSSRW LCCIGSNRDS AFGPQYQSSL
CNKSCFCGVE SSGKLQFRDI TRAYALLWKH FVQAYADHRV LKWSLWWALG TCGYLQVANY
MQLLWLDTVH SNDEIYNGAV DFAYAILGAI TVFSVGKIRL NWDLLGDISL SMFSFLCGAI
MVVSSYSYNI WFLYAGYIIF GVIYHTMVTV ASFEVAKYIC EDSYGLIFGI NIFIALVAQS
LFTLVVVNAL MLNIRWQYFI YGSYFVILGF MYFLMGILNI VKYYQSNERF NLWTSDETQS
TVTQTTNDMR DNGASAAVEE NGN
//
