ID E2BKW7_HARSA Unreviewed; 533 AA.
AC E2BKW7;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Glucose dehydrogenase [acceptor] {ECO:0000313|EMBL:EFN83663.1};
GN ORFNames=EAI_01051 {ECO:0000313|EMBL:EFN83663.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN83663.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN83663.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR EMBL; GL448836; EFN83663.1; -; Genomic_DNA.
DR RefSeq; XP_011140803.1; XM_011142501.2.
DR AlphaFoldDB; E2BKW7; -.
DR STRING; 610380.E2BKW7; -.
DR InParanoid; E2BKW7; -.
DR OMA; GINYMMY; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF154; FI04917P; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 2.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2, ECO:0000256|RuleBase:RU003968};
KW Flavoprotein {ECO:0000256|RuleBase:RU003968};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237}.
FT DOMAIN 82..105
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT BINDING 84
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 533 AA; 59499 MW; C7E6594452B8C686 CRC64;
MQQYDYIVVG AGSAGAILAA HLAEDEHKVL LLEAGGTAPP FLSIPLLAPA IQKTVYDWQY
VTVPQKYACR GLINNQSIWP RGKVLGGSSR LNYMAYVLGH KLDYEEWFPD FLQTVAENND
SVSTSELRWQ SDFANVILEA IKELNYDIGN MNKKLTTGFM KVQLTMENGE RWSSEKILHK
KCKYSPVILT HTFATKVLVN LNKAEGIEFV RFGSKYTAVA KKGVILSAGV IESPKLLMLS
GIGPRKHLND LNIHVINDLP VGQNLVDHIL TGVDLVTLNV SLGLNLFQIL NPVSALNYFL
FGRGQWTSTA IEVLGTFHSV ANKNKSAIPD LQLMVLSLGI SNDNGIIFKK AMGFSDEVYN
KYFTPLLYEN TIIIAPILLH PKSSGELRLR SNNPFDKPLI DPQYLSNEDD IETLVEGLYF
VKDLLETNAL RAYSASLNKK SFPGCENETF DTREYWRCYM RHLTLTAYHP AGTCRMGDVV
DTSFKVHNMT NLYVVDASVL PLLPSGNINA AVIALAQKAS RIFRNEKIKE KEV
//
