ID E2BX23_HARSA Unreviewed; 820 AA.
AC E2BX23;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Probable G-protein coupled receptor 158 {ECO:0000313|EMBL:EFN79742.1};
GN ORFNames=EAI_16319 {ECO:0000313|EMBL:EFN79742.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN79742.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN79742.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR EMBL; GL451202; EFN79742.1; -; Genomic_DNA.
DR AlphaFoldDB; E2BX23; -.
DR InParanoid; E2BX23; -.
DR OMA; AIEFNFH; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd15293; 7tmC_GPR158-like; 1.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR043458; GPR158/179.
DR PANTHER; PTHR32546; G-PROTEIN COUPLED RECEPTOR 158-RELATED; 1.
DR PANTHER; PTHR32546:SF16; G-PROTEIN COUPLED RECEPTOR CG31760-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EFN79742.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..820
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003158453"
FT TRANSMEM 397..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 619..638
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 399..646
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 162..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 773..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 678..705
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 259..281
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..820
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 820 AA; 90964 MW; DF21F9657404E67D CRC64;
MAESWLSVTV TTMTMMACVT LTRATDPSSS APLTTTVRDD LPLDSKRAAI EEALDVIEAA
STGSLGEVCV NTAGFKSLPA GVELDPRRYD AARQKADMTA MVLQNFGAAE ATRRNALLDA
LTKSLLVSVN DAVEARVIAL NASTGTVIAA VWLKRSPGSV GEPTKVENHA LQPGSQPDPS
LPWFENAGGS TELRSPKFMQ SPPIESYRGW WTIPYFSCKT RRWLISYSVN VKSPDVRPGV
REFISMDVDI SGLEVNQGDA PPPPLPPPLP PPPPPPSRDG NDGVEPPASN QIAFFKGTHK
CHTDTTQCVY QGPDNRVNEN GVGAGWSKGA YACKCRQGFY SVSHQRAGFD GILVEAAWKE
MKENRSDSYE RVFRCSRCAP GCARCKGPEP CLATYNWPFR ITLLAVSIFC AFGTIVLVAY
MYQHRKLKVF KVASPIFLSI TLLGCALMYL EMAAIFPVLD MYSCIATKWT RHMGFCVSYT
ALLMKTWGVS LTYRVKSAHK VKLTDKQLLQ WMVPILLVML IYLGTWTLSA PPYAEVIADN
HDLKFYQCSY NWWDHSLAIG EILFLAWGIK VCYNVRNAES LFNEARLISY AIYNIAAVNI
TMIAIHLLIF PHAGPDIKYL LGFLRTQFST SVTILLVFGP KVIRVLRGQG DQWDSRARAR
GVTASFSLNG IGLVPEETTD LYQENEELKE EIQKLAARIE FMKIVHMEMH NRHIKPKMGG
YFSTHGHGHG HPSTGQSPIA KSSTASFILK TAVERGATAA AAAAVEDSTF PSGSLHRARR
MEMLKERKAE RERERNKEKE QKEKSQQEKQ QERRSSGEKV
//
