ID E2C7K8_HARSA Unreviewed; 750 AA.
AC E2C7K8;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Spermatogenesis-associated protein 13 {ECO:0000313|EMBL:EFN76084.1};
DE Flags: Fragment;
GN ORFNames=EAI_03886 {ECO:0000313|EMBL:EFN76084.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN76084.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN76084.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
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DR EMBL; GL453383; EFN76084.1; -; Genomic_DNA.
DR AlphaFoldDB; E2C7K8; -.
DR STRING; 610380.E2C7K8; -.
DR EnsemblMetazoa; XM_025300367.1; XP_025156152.1; LOC105190846.
DR InParanoid; E2C7K8; -.
DR OMA; FEQTMDE; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd01224; PH_Collybistin_ASEF; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd11828; SH3_ARHGEF9_like; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45834:SF3; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L; 1.
DR PANTHER; PTHR45834; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR00499; P67PHOX.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 252..311
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 347..531
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 562..668
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFN76084.1"
SQ SEQUENCE 750 AA; 85338 MW; D736D5EE8E1052D2 CRC64;
RFGPLVWRSS KERKKGNKAA RNAKCNSGDS GIQIEMVSGG ALTGGSGGGV MGGGDSSESH
DTDDIPDDTD SPPALRRRVA DKLRPQSELI NQILIDKFKA DLQSRASRHN HVRRTNSDLG
GQRLLQWDTR SGYVHNYRRM LSTPSPIKTR PPRLSPRHSS HDIVTLRSNA KGRSSRTNLR
RSLSQPLGIN QLSPLMRTKT AGVRLPGGNV LSEDEQDGRA GTSDDEMMSD SESSVASLTD
RKKSLEQTMD EDVAILAEAV WDHVAMETEE LAFRAGDVID VLDTLDKDWW WGSCRGIHGW
FPAAFVRLRV SQEDTVEDCL AAMASGVSSA TQLRRRTSVS LLSNEQVRTS VVRELVQTER
DFVKVLRDVA EGYIAECRRH TDMFTEEQIE TIFINLEELL DFQSEFLKDL EACIDWNAPH
KSCVGECFLN HRAGFRMYSE YCNSHPMAMA TLQELYQHNR YSKFFEACRL MRGLIEIPLD
GYLLTPVQRI CKYPLQLAEL FKYTKTDHPD YHKIQEALEA MRGVAVLINE RKRRMESLEK
LAAWQMRVEG WEGEDLIEVS SQLIYQGEAM RVTTGMWTNN ITLFLFDHQL VYCKKDILKR
NTYVYKGRIY LDTSEVIDVP DGKDLQSGVT VRHCLKVYSC VRDKWLLFCC RTADEKRRWL
AAMAEERRLV AQDRNDGLEF PAAARQLARL AARRQQNRPP IKPRNKTYKR ESTYEMPAMV
AQGTTNSLGR KVGTWFTFGS SKKSTRLQPS
//
