ID E2C8G9_HARSA Unreviewed; 619 AA.
AC E2C8G9;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
GN ORFNames=EAI_09699 {ECO:0000313|EMBL:EFN75699.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN75699.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN75699.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR EMBL; GL453666; EFN75699.1; -; Genomic_DNA.
DR AlphaFoldDB; E2C8G9; -.
DR STRING; 610380.E2C8G9; -.
DR EnsemblMetazoa; XM_025298588.1; XP_025154373.1; LOC105191072.
DR InParanoid; E2C8G9; -.
DR OMA; VQWMRDQ; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07792; FGGY_GK1-3_metazoa; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR042018; GK1-3_metazoa.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF40; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:EFN75699.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 81..334
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 349..534
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 68856 MW; B7B4DF761283416C CRC64;
MEQEDPNGNA TTRQDANKNA TEEVAHKRDA QAEEDSLGSP RVPLEMEQSE TGRRTSIFKY
YSYKNADTMS STVKKTGPSV GVIDVGTRTV RFVVFNAKHV AEIASHQIDI EQINPKEGWM
EQDPKEILFA VKTCVKEVIR KFDVLGMKID EIVTVGITNQ RETTIAWDAS TGDPLYNAIV
WSDIRTDSMV DQIIAKFPDK SKNHLKPLCG LPVSPYFSAL KIRWLKEHVP AVKKAIREKR
CKVGTVDTWI VWNLTGGKDG GLYITDVTNA SRTMLMNIET LSWDPTLCRY FDIPMQMLPE
IRSSSEIYGK VSTGPLADIP ISGILGNQQS ALVGQNCLKK GQAKNTYRSG CFLLCNTGHT
RVYSSHGLVT TVAYQLGPNS PAVYALEGSV AVAGAAIKWL RDNMKLIKDV HESEHLAQSV
FSTGDVYFVP AFTGLYAPYW RKDARGIICG LTAFTTKQHI IRASLEAVCF QTRDILEAMY
KDCGFPLTKL NTDGKMSTNN LLMQLQADLC GTPVFRSTMP DITALGVAMA AGHAEGIDVW
ELEGEDVETV PTDTFLPTTT PEERDARYKK WKMAVERSLG WAAMKMSDQM TGKFRNAEKL
KPEIPDVPLC KYVRLCVCK
//
