ID   E2LFG3_MONPE            Unreviewed;       138 AA.
AC   E2LFG3;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
DE   Flags: Fragment;
GN   ORFNames=MPER_05132 {ECO:0000313|EMBL:EEB95838.1};
OS   Moniliophthora perniciosa (strain FA553 / isolate CP02) (Witches'-broom
OS   disease fungus) (Marasmius perniciosus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX   NCBI_TaxID=554373 {ECO:0000313|EMBL:EEB95838.1, ECO:0000313|Proteomes:UP000000741};
RN   [1] {ECO:0000313|EMBL:EEB95838.1, ECO:0000313|Proteomes:UP000000741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FA553 / isolate CP02 {ECO:0000313|Proteomes:UP000000741};
RX   PubMed=19019209; DOI=10.1186/1471-2164-9-548;
RA   Mondego J.M., Carazzolle M.F., Costa G.G., Formighieri E.F., Parizzi L.P.,
RA   Rincones J., Cotomacci C., Carraro D.M., Cunha A.F., Carrer H., Vidal R.O.,
RA   Estrela R.C., Garcia O., Thomazella D.P., de Oliveira B.V., Pires A.B.,
RA   Rio M.C., Araujo M.R., de Moraes M.H., Castro L.A., Gramacho K.P.,
RA   Goncalves M.S., Neto J.P., Neto A.G., Barbosa L.V., Guiltinan M.J.,
RA   Bailey B.A., Meinhardt L.W., Cascardo J.C., Pereira G.A.;
RT   "A genome survey of Moniliophthora perniciosa gives new insights into
RT   Witches' broom disease of cacao.";
RL   BMC Genomics 9:548-548(2008).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEB95838.1}.
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DR   EMBL; ABRE01008981; EEB95838.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2LFG3; -.
DR   STRING; 554373.E2LFG3; -.
DR   KEGG; mpr:MPER_05132; -.
DR   HOGENOM; CLU_151057_0_0_1; -.
DR   InParanoid; E2LFG3; -.
DR   OrthoDB; 25690at2759; -.
DR   Proteomes; UP000000741; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR23176:SF140; ATYPICAL_BCR PROTEIN KINASE; 1.
DR   PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000741};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..84
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          81..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EEB95838.1"
SQ   SEQUENCE   138 AA;  15010 MW;  297BDBF161E66740 CRC64;
     FVDPQERIRE LSRLIGSLPI ANYSLLRALT AHLILIVQNS AANKMTMRNV GIVFSPTLGI
     PAGVFSLMLG EFNRVFNVDG DKATEEPAPP GEGQANEPDR RNSRQYSEAA ADQLLGLRGR
     TLAVPPPDDN HSDTDDLS
//