ID   E2PXP7_STRCL            Unreviewed;       515 AA.
AC   E2PXP7;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Lecithin:cholesterol acyltransferase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SCLAV_3066 {ECO:0000313|EMBL:EFG08137.1};
OS   Streptomyces clavuligerus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1901 {ECO:0000313|EMBL:EFG08137.1, ECO:0000313|Proteomes:UP000002357};
RN   [1] {ECO:0000313|EMBL:EFG08137.1, ECO:0000313|Proteomes:UP000002357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 /
RC   NRRL 3585 / VKM Ac-602 {ECO:0000313|Proteomes:UP000002357};
RX   PubMed=20624727; DOI=10.1093/gbe/evq013;
RA   Medema M.H., Trefzer A., Kovalchuk A., van den Berg M., Mueller U.,
RA   Heijne W., Wu L., Alam M.T., Ronning C.M., Nierman W.C., Bovenberg R.A.L.,
RA   Breitling R., Takano E.;
RT   "The sequence of a 1.8-mb bacterial linear plasmid reveals a rich
RT   evolutionary reservoir of secondary metabolic pathways.";
RL   Genome Biol. Evol. 2:212-224(2010).
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DR   EMBL; CM000913; EFG08137.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2PXP7; -.
DR   STRING; 1901.BB341_13270; -.
DR   eggNOG; COG1075; Bacteria.
DR   Proteomes; UP000002357; Chromosome.
DR   GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR003386; LACT/PDAT_acylTrfase.
DR   PANTHER; PTHR11440:SF97; BCDNA.GH02384; 1.
DR   PANTHER; PTHR11440; LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF02450; LCAT; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002357}.
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   515 AA;  54893 MW;  5C5D12317077B518 CRC64;
     MPERPQPDTA NQRPRPPSPD PPPVSPNATQ DAVVVVPGIM GSELYDTEQD RVVWGLSDSR
     WLLRAWTLPG GLDRLHVTPE EREGRLGRIR ARRLLRVPAW SPVLRGVEPY GALVRTVTRS
     AASPDAVLEF PYDWRLPVAV NARLLAGAAR AHLERWRRHP AHTAARRHRV DEREGRLVFV
     AHSMGGLLTL AALRDGPDAD LARDTRGVLT LGTPFRGAVA AAVILNSGRG APVPLPHGRL
     RRLAATMPGL HDLLPSFTCL GEGADARKPT PSDIVALGGD EELARRSREL HERLAAHPLP
     GHRAVIGVSQ PTAQSLELRQ GVVVPHELSY RHHGDGGLMR HENGAPRRFD VGGDGTVHKE
     SAALTRSSVP FALQHGSLAK GEAALEAVTS FLEEDEHLGP PQAAARLGLQ VPDFVAPGKR
     WTLRVHGADG PAGLDCVVEK VAEESAPGGA FRVRAALYGD DEDDRSGGGS GDALAARVAV
     PSEGLYRVSL DSGDGAPLSQ LVLAGADGPP AEAEA
//