ID E2RU02_GIAIC Unreviewed; 133 AA.
AC E2RU02;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=[2Fe-2S] ferredoxin {ECO:0000313|EMBL:EDO77857.1};
GN ORFNames=GL50803_0027266 {ECO:0000313|EMBL:KAE8302005.1},
GN GL50803_27266 {ECO:0000313|EMBL:EDO77857.1};
OS Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=184922 {ECO:0000313|EMBL:EDO77857.1};
RN [1] {ECO:0000313|EMBL:EDO77857.1, ECO:0000313|Proteomes:UP000001548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50803 / WB clone C6 {ECO:0000313|Proteomes:UP000001548},
RC and WB C6 {ECO:0000313|EMBL:EDO77857.1};
RX PubMed=17901334; DOI=10.1126/science.1143837;
RA Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E., Palm D.,
RA Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA Svard S.G., Sogin M.L.;
RT "Genomic minimalism in the early diverging intestinal parasite Giardia
RT lamblia.";
RL Science 317:1921-1926(2007).
RN [2] {ECO:0000313|EMBL:KAE8302005.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB C6 {ECO:0000313|EMBL:KAE8302005.1};
RA Xu F., Jex A., Svard S.G.;
RT "New Giardia intestinalis WB genome in near-complete chromosomes.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- SIMILARITY: Belongs to the adrenodoxin/putidaredoxin family.
CC {ECO:0000256|ARBA:ARBA00010914}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDO77857.1}.
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DR EMBL; AACB02000033; EDO77857.1; -; Genomic_DNA.
DR EMBL; AACB03000004; KAE8302005.1; -; Genomic_DNA.
DR RefSeq; XP_001705531.1; XM_001705479.1.
DR AlphaFoldDB; E2RU02; -.
DR STRING; 184922.E2RU02; -.
DR EnsemblProtists; EDO77857; EDO77857; GL50803_27266.
DR GeneID; 5698404; -.
DR KEGG; gla:GL50803_0027266; -.
DR VEuPathDB; GiardiaDB:GL50803_27266; -.
DR HOGENOM; CLU_082632_5_0_1; -.
DR InParanoid; E2RU02; -.
DR OMA; TPMEEDM; -.
DR Proteomes; UP000001548; Chromosome 2.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0009055; F:electron transfer activity; IBA:GO_Central.
DR GO; GO:0022900; P:electron transport chain; IBA:GO_Central.
DR GO; GO:0140647; P:P450-containing electron transport chain; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR001055; Adrenodoxin.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR PANTHER; PTHR23426:SF34; FERREDOXIN-2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR23426; FERREDOXIN/ADRENODOXIN; 1.
DR Pfam; PF00111; Fer2; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW Reference proteome {ECO:0000313|Proteomes:UP000001548}.
FT DOMAIN 11..112
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
SQ SEQUENCE 133 AA; 14511 MW; 1F98B555FFFE12B9 CRC64;
MSLLSSIRRF ITFRVVQQGV EHTVSGAVGQ SLLDAIKAAH IPIQDACEGH LGCGTCGVYL
DKKTYKRIPR ATKEEAVLLD QVPNPKPTSR LSCAVKLSSM LEGATVRIPS FNKNVLSESD
ILASEEKKRH GQH
//
