ID E2S7Y2_9ACTN Unreviewed; 338 AA.
AC E2S7Y2;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Transcriptional regulator, HxlR family {ECO:0000313|EMBL:EFQ84798.1};
GN ORFNames=HMPREF0063_10139 {ECO:0000313|EMBL:EFQ84798.1};
OS Aeromicrobium marinum DSM 15272.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=585531 {ECO:0000313|EMBL:EFQ84798.1, ECO:0000313|Proteomes:UP000003111};
RN [1] {ECO:0000313|EMBL:EFQ84798.1, ECO:0000313|Proteomes:UP000003111}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15272 {ECO:0000313|EMBL:EFQ84798.1,
RC ECO:0000313|Proteomes:UP000003111};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFQ84798.1}.
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DR EMBL; ACLF03000001; EFQ84798.1; -; Genomic_DNA.
DR RefSeq; WP_007076706.1; NZ_CM001024.1.
DR AlphaFoldDB; E2S7Y2; -.
DR STRING; 585531.HMPREF0063_10139; -.
DR eggNOG; COG1733; Bacteria.
DR HOGENOM; CLU_068247_0_0_11; -.
DR Proteomes; UP000003111; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR002577; HTH_HxlR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33204; TRANSCRIPTIONAL REGULATOR, MARR FAMILY; 1.
DR PANTHER; PTHR33204:SF36; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF01638; HxlR; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51118; HTH_HXLR; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000003111};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 20..122
FT /note="HTH hxlR-type"
FT /evidence="ECO:0000259|PROSITE:PS51118"
FT DOMAIN 187..285
FT /note="HTH hxlR-type"
FT /evidence="ECO:0000259|PROSITE:PS51118"
SQ SEQUENCE 338 AA; 37424 MW; 1D4A99D66997E7B4 CRC64;
MTLDLDGGSA ELATHPTRLE PGATNAVGRM LGLLGDEWTL LILRQALQGV GRFGQLMDAL
PISNSVLTGR LNLLVREGLL RRNVYQTNPL RAEYVVTPRS RALWPFMLAI WEWERQWVQD
HADGLPAMHH DTCGHDFSPL MSCGGCGKAV EAKDVAAEWG PSGAWSRSVP ESATRRRSDA
EVVRSTAGLF PETMMIFGNR WASALLGAAF RGVTRFSDFE ANLAAPPTLV ADRLRAFCAI
GVLSATQNDR RPDWVEYRLT AKGRAFYPVV AASLQWAEDW FVAPEGPALV QVHRACDEPF
VATFRCDQCH EVLHGHEISI VPREEPGDDT PSRREDPR
//
