ID E2S8X5_9ACTN Unreviewed; 363 AA.
AC E2S8X5;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=alpha-amylase {ECO:0000256|ARBA:ARBA00012595};
DE EC=3.2.1.1 {ECO:0000256|ARBA:ARBA00012595};
GN ORFNames=HMPREF0063_10483 {ECO:0000313|EMBL:EFQ84630.1};
OS Aeromicrobium marinum DSM 15272.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=585531 {ECO:0000313|EMBL:EFQ84630.1, ECO:0000313|Proteomes:UP000003111};
RN [1] {ECO:0000313|EMBL:EFQ84630.1, ECO:0000313|Proteomes:UP000003111}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15272 {ECO:0000313|EMBL:EFQ84630.1,
RC ECO:0000313|Proteomes:UP000003111};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in
CC polysaccharides containing three or more (1->4)-alpha-linked D-
CC glucose units.; EC=3.2.1.1; Evidence={ECO:0000256|ARBA:ARBA00000548};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFQ84630.1}.
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DR EMBL; ACLF03000002; EFQ84630.1; -; Genomic_DNA.
DR RefSeq; WP_007079361.1; NZ_CM001024.1.
DR AlphaFoldDB; E2S8X5; -.
DR STRING; 585531.HMPREF0063_10483; -.
DR eggNOG; COG1404; Bacteria.
DR HOGENOM; CLU_753620_0_0_11; -.
DR OrthoDB; 3750238at2; -.
DR Proteomes; UP000003111; Chromosome.
DR GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013784; Carb-bd-like_fold.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001119; SLH_dom.
DR PANTHER; PTHR43308:SF4; OUTER MEMBRANE PROTEIN ALPHA; 1.
DR PANTHER; PTHR43308; OUTER MEMBRANE PROTEIN ALPHA-RELATED; 1.
DR Pfam; PF00395; SLH; 3.
DR SUPFAM; SSF49452; Starch-binding domain-like; 1.
DR PROSITE; PS51272; SLH; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003111};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..363
FT /note="alpha-amylase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038977372"
FT DOMAIN 163..230
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 234..297
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 301..363
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
SQ SEQUENCE 363 AA; 39578 MW; EFE16D73F103E703 CRC64;
MKRNRTRTRR LSVAAVAAAL VVTGWVAAPV QAEVNDTGAV SGTVFGRAIG STAETVPGVP
VTVLQLDEDS GTFEPVPGAT DVTDGDGDYL IDGLPEGDYR LCFGSPGQIV ASRWISSCYR
NAYSVDQARD IEVGPGEVNS LQLSESLLPA FTDVALPLSV EQESLDGRAA VGGHPFWSEI
TDLALFGVTT GYDEADGSRT FRPGQPVLRE QMAAFLYRTE KLETGMEPEV DLPEVSPFTD
VPTTHVFYRE IVWLADRRIT TGYFDGTFRP GQPVLREQMA AFLYRFDGSE FEDGDGADDV
GPEFTDVNSA NNVFFDEIEW MALEGITTGY DEGNGTRTFR PAQPVLREQM AAFLIRFAEP
LIN
//
