ID E2S8Z3_9ACTN Unreviewed; 546 AA.
AC E2S8Z3;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Ser/Thr phosphatase family protein {ECO:0000313|EMBL:EFQ84648.1};
GN ORFNames=HMPREF0063_10501 {ECO:0000313|EMBL:EFQ84648.1};
OS Aeromicrobium marinum DSM 15272.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=585531 {ECO:0000313|EMBL:EFQ84648.1, ECO:0000313|Proteomes:UP000003111};
RN [1] {ECO:0000313|EMBL:EFQ84648.1, ECO:0000313|Proteomes:UP000003111}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15272 {ECO:0000313|EMBL:EFQ84648.1,
RC ECO:0000313|Proteomes:UP000003111};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. YfcE
CC family. {ECO:0000256|ARBA:ARBA00008950}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFQ84648.1}.
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DR EMBL; ACLF03000002; EFQ84648.1; -; Genomic_DNA.
DR AlphaFoldDB; E2S8Z3; -.
DR STRING; 585531.HMPREF0063_10501; -.
DR eggNOG; COG1408; Bacteria.
DR HOGENOM; CLU_558765_0_0_11; -.
DR Proteomes; UP000003111; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00838; MPP_superfamily; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR024654; Calcineurin-like_PHP_lpxH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR Pfam; PF12850; Metallophos_2; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003111};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 129..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 273..441
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF12850"
FT REGION 523..546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..546
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 546 AA; 56931 MW; 317A1433DC5D7248 CRC64;
MARGVEGRAA TVRRLVAAAV LLAVAVPTGL GVARASFLAS EQSVSIGAHD ATVRPNFTSA
AVLEAGPLLP QLRLPLDDTP LGIGARIELG GSEARSLDEV ITNDAVIASQ PEGEIAAVTE
AIGQMARQAV LRGVGVALLV SAALVVAWRA VGADRRAALA RSWRRPSRGQ GAAGAGVLAT
VLAGGVLVAV SSPAIPDQDV SWIPVTDVFT TLPDDPILDR LELSDGAATR SGRSLIEGAL
RTYRESNAFY DRLVETAEDV EVRTPEEGQT TALVVTDRHS NVAMDPVARQ LAENAEAELL
IDLGDDTSNG ASWEQFSINS LAREFEGFDV VAVAGNHDQG PIIPDLMQRR GFELLAGEPK
DVAGIRFLGA SDPRSSGLTQ GYTGDESDNI AAIRDQDAEL TRTACDDGDV AVVAVHSSAQ
ARQLRESGCV DLVLSGHLHR QVGPDVTITD DGEATVSLTT GTTGGAVYAF ALGTGLRREA
QMTLVTFEDG RPVGLQIIDV QPGGTISVQE YVTLADLIEA AVAGDPELDP DVPLPPEPEP
EPEPTG
//
