ID   E2SFM6_9ACTN            Unreviewed;       317 AA.
AC   E2SFM6;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=F420-0:gamma-glutamyl ligase {ECO:0000313|EMBL:EFQ81993.1};
GN   Name=cofE {ECO:0000313|EMBL:EFQ81993.1};
GN   ORFNames=HMPREF0063_12835 {ECO:0000313|EMBL:EFQ81993.1};
OS   Aeromicrobium marinum DSM 15272.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Aeromicrobium.
OX   NCBI_TaxID=585531 {ECO:0000313|EMBL:EFQ81993.1, ECO:0000313|Proteomes:UP000003111};
RN   [1] {ECO:0000313|EMBL:EFQ81993.1, ECO:0000313|Proteomes:UP000003111}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15272 {ECO:0000313|EMBL:EFQ81993.1,
RC   ECO:0000313|Proteomes:UP000003111};
RA   Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA   Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA   Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA   Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA   Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA   Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA   Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA   Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA   Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA   Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA   Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA   Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA   Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA   Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA   Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFQ81993.1}.
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DR   EMBL; ACLF03000013; EFQ81993.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2SFM6; -.
DR   STRING; 585531.HMPREF0063_12835; -.
DR   eggNOG; COG1478; Bacteria.
DR   HOGENOM; CLU_051152_0_0_11; -.
DR   OrthoDB; 9788295at2; -.
DR   Proteomes; UP000003111; Chromosome.
DR   GO; GO:0043773; F:coenzyme F420-0 gamma-glutamyl ligase activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1330.100; CofE-like; 2.
DR   InterPro; IPR008225; F420-0_g-glutamyl_ligase.
DR   InterPro; IPR002847; F420-0_gamma-glut_ligase-dom.
DR   NCBIfam; TIGR01916; F420_cofE; 1.
DR   PANTHER; PTHR47917; -; 1.
DR   PANTHER; PTHR47917:SF1; COENZYME F420:L-GLUTAMATE LIGASE; 1.
DR   Pfam; PF01996; F420_ligase; 2.
DR   SUPFAM; SSF144010; CofE-like; 1.
PE   4: Predicted;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:EFQ81993.1};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Potassium {ECO:0000256|ARBA:ARBA00022958};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003111}.
FT   DOMAIN          12..50
FT                   /note="Coenzyme F420:L-glutamate ligase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01996"
FT   DOMAIN          62..202
FT                   /note="Coenzyme F420:L-glutamate ligase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01996"
SQ   SEQUENCE   317 AA;  31907 MW;  D9814ACC2A2F2638 CRC64;
     MMSLTFTAVE GIGEIVPGDD LGRIIASAAP DLADGDVVVV TSKVVAKAAG LATSGSREDL
     LAEQTDRAVA TRGDTRIVRT HHGLTLAAAG IDASNTSAGT LLPLPVDPDG DARAIRARLA
     ELTGRRVAVV VSDTAGRAWR HGQTDIAIGC AGLEPLESFA GRTDPHGNRL VVTAPAVADE
     IAGAAELASG KLGGRPVVVV RGVPAHLLTA GDGPGATALV RAEDDDLFGL GARDAVVAAV
     AADGASVRGF TPTTITPAAL VELAGVPVGI GVDVDGDLVR VAAPTDHLVA AGAVQQRLLT
     LATAHRVVVR VEVEHLT
//