ID E2ZBV2_9FIRM Unreviewed; 672 AA.
AC E2ZBV2;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Penicillin-binding protein, transpeptidase domain protein {ECO:0000313|EMBL:EFQ04330.1};
GN ORFNames=HMPREF9429_00934 {ECO:0000313|EMBL:EFQ04330.1};
OS Megasphaera micronuciformis F0359.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Megasphaera.
OX NCBI_TaxID=706434 {ECO:0000313|EMBL:EFQ04330.1, ECO:0000313|Proteomes:UP000003195};
RN [1] {ECO:0000313|EMBL:EFQ04330.1, ECO:0000313|Proteomes:UP000003195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0359 {ECO:0000313|EMBL:EFQ04330.1,
RC ECO:0000313|Proteomes:UP000003195};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFQ04330.1}.
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DR EMBL; AECS01000036; EFQ04330.1; -; Genomic_DNA.
DR AlphaFoldDB; E2ZBV2; -.
DR STRING; 706434.HMPREF9429_00934; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_0_9; -.
DR Proteomes; UP000003195; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000003195};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 613..672
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 672 AA; 72954 MW; 1F0C31A0B6103D78 CRC64;
MDKEQLQQKK EQKKDMKMRK RILKCFTGLL IFGLVLTVRL VCLQTVQSAD LTERADAQSE
ADRKIQSPRG MILDRDGKVL AISEVAKSLY ADPTMMQSDT DGKGKTPAEA AELLAPYLRI
KQDEIEERLS RDTSFVWLDR TMDDDKYQAL KSVIADKHIK GLRFVDENRR YYPNGTLAAQ
LIGFVGDNDH GLDGIEMVLD DDIRGDTQKL RLTTDSNNVP IFDSALEKVL PDKEKSVRLT
IDSTIQYIAE KGLDDIMKNN KPEGAAIIIM NPKTGEILAM ASRPNFDPND YGKANKEAYK
NRAVVNLYEP GSTFKPLMAS AALDAGTWTE SKTYKDVGYV QVDDRVISNW DDSGMGTVTL
KEILKFSINT GMVAIGLNTG GKILTSYAEK YGFGKQTGIE LPGEGEGILF NPDEMSNINT
ATMAIGQGIA VTPLQMVQAF GAVANHGTMM KPFVIKEIDN PDGSVFKKTE PQEVGQPISA
EVSRIISTIM ADEINSGGGL NAKIDGYNFC GKTGTAQRLN SEGTGYAEGQ YIGSFVGFGP
LEDPEYVVLI VVDNPSGVYY GAQVAAPIFK MMMTDIVRIK GIRPASAAAA NATVLKSLPA
AASRAPLPPV DVTGDTVLLP SFIGYDSREV NEWLNAAGLG FIPNGTGLAT YQVPAAGTYV
DAGSNVTVSF SR
//
