ID   E2ZFJ2_9FIRM            Unreviewed;       266 AA.
AC   E2ZFJ2;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   SubName: Full=Transcriptional regulator, GntR family {ECO:0000313|EMBL:EFQ08055.1};
GN   ORFNames=HMPREF9436_00425 {ECO:0000313|EMBL:EFQ08055.1};
OS   Faecalibacterium cf. prausnitzii KLE1255.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=748224 {ECO:0000313|EMBL:EFQ08055.1, ECO:0000313|Proteomes:UP000006028};
RN   [1] {ECO:0000313|EMBL:EFQ08055.1, ECO:0000313|Proteomes:UP000006028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KLE1255 {ECO:0000313|EMBL:EFQ08055.1,
RC   ECO:0000313|Proteomes:UP000006028};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFQ08055.1}.
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DR   EMBL; AECU01000027; EFQ08055.1; -; Genomic_DNA.
DR   AlphaFoldDB; E2ZFJ2; -.
DR   STRING; 748224.HMPREF9436_00425; -.
DR   eggNOG; COG1802; Bacteria.
DR   HOGENOM; CLU_017584_5_2_9; -.
DR   OrthoDB; 154206at2; -.
DR   BioCyc; FCF748224-HMP:GTSS-3024-MONOMER; -.
DR   Proteomes; UP000006028; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43537:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RSPR; 1.
DR   PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          43..110
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   266 AA;  30907 MW;  D4FA4A43638BD39E CRC64;
     MISDVCGAVR PAVKLRQAKK GTAMREEKAS ALPLLLDVRR MDENNRAYAY RMLRKNIMTL
     QLQPGCQLSE AELCEQLAMS RTPVHEALMM LKSEWLVDVL PQRGSIVSKI SVPYLNEGFA
     MRRILEPALL RGLAGKLTRE QLNEFQELLN RQNEDLYLDQ DAADDFFISL DNDFHRLLYH
     DSGYDRIWEA MHNVTSHMDR VRYLDSALCR GNIASVQKEH EQIFGYLRDG LPLDVDVEAL
     FEHHLGMYRE NFQKILERFP DFFVQT
//